Cerebellar pleomorphic xanthoastrocytoma
Pleomorphic xanthoastrocytoma (PXA) is a relatively rare neoplasm predominantly occurring in the supratentorial compartment. Among the unusual locations, cerebellum is the most common with few cases reported in the spinal cord and retina. The infratentorial PXA has a female preponderance, occurs in...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2013-09-01
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| Series: | Indian Journal of Neurosurgery |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.124243 |
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| author | Raghavendra Harpanahalli Bhaskar Suryanarayanan Minakshi Bhardwaj L.N. Gupta |
| author_facet | Raghavendra Harpanahalli Bhaskar Suryanarayanan Minakshi Bhardwaj L.N. Gupta |
| author_sort | Raghavendra Harpanahalli |
| collection | DOAJ |
| description | Pleomorphic xanthoastrocytoma (PXA) is a relatively rare neoplasm predominantly occurring in the supratentorial compartment. Among the unusual locations, cerebellum is the most common with few cases reported in the spinal cord and retina. The infratentorial PXA has a female preponderance, occurs in the fourth decade of life and is composite in 2/3rd of the cases as compared to the supratentorial lesions. Gross total surgical excision is the goal, but is difficult due to the infiltration of the lesion into brainstem/upper cervical cord. Adjuvant radio/chemotherapy for recurrent/progressive/malignant forms have been, reported, but with variable results. This case is of a 25-year-old man who had a cerebellar PXA extending into the upper cervical cord that was sub-totally excised. |
| format | Article |
| id | doaj-art-9d6cc5ea1ab940d0ab90e11423cfb28e |
| institution | OA Journals |
| issn | 2277-954X 2277-9167 |
| language | English |
| publishDate | 2013-09-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Neurosurgery |
| spelling | doaj-art-9d6cc5ea1ab940d0ab90e11423cfb28e2025-08-20T01:59:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672013-09-01020330130410.4103/2277-9167.124243Cerebellar pleomorphic xanthoastrocytomaRaghavendra HarpanahalliBhaskar SuryanarayananMinakshi Bhardwaj0L.N. GuptaPathology, PGIMER and Dr. RML HospitalPleomorphic xanthoastrocytoma (PXA) is a relatively rare neoplasm predominantly occurring in the supratentorial compartment. Among the unusual locations, cerebellum is the most common with few cases reported in the spinal cord and retina. The infratentorial PXA has a female preponderance, occurs in the fourth decade of life and is composite in 2/3rd of the cases as compared to the supratentorial lesions. Gross total surgical excision is the goal, but is difficult due to the infiltration of the lesion into brainstem/upper cervical cord. Adjuvant radio/chemotherapy for recurrent/progressive/malignant forms have been, reported, but with variable results. This case is of a 25-year-old man who had a cerebellar PXA extending into the upper cervical cord that was sub-totally excised.http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.124243cerebellumpleomorphic xanthoastrocytomaspinal cord |
| spellingShingle | Raghavendra Harpanahalli Bhaskar Suryanarayanan Minakshi Bhardwaj L.N. Gupta Cerebellar pleomorphic xanthoastrocytoma Indian Journal of Neurosurgery cerebellum pleomorphic xanthoastrocytoma spinal cord |
| title | Cerebellar pleomorphic xanthoastrocytoma |
| title_full | Cerebellar pleomorphic xanthoastrocytoma |
| title_fullStr | Cerebellar pleomorphic xanthoastrocytoma |
| title_full_unstemmed | Cerebellar pleomorphic xanthoastrocytoma |
| title_short | Cerebellar pleomorphic xanthoastrocytoma |
| title_sort | cerebellar pleomorphic xanthoastrocytoma |
| topic | cerebellum pleomorphic xanthoastrocytoma spinal cord |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/2277-9167.124243 |
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