A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review

Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged...

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Main Authors: Olivia Allen, Ahmed Edhi, Adam Hafeez, Alexandra Halalau
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2018/3625139
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author Olivia Allen
Ahmed Edhi
Adam Hafeez
Alexandra Halalau
author_facet Olivia Allen
Ahmed Edhi
Adam Hafeez
Alexandra Halalau
author_sort Olivia Allen
collection DOAJ
description Hepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. In addition, extrahepatic manifestations have been reported, including urticarial and maculopapular rash, acute kidney injury, autoimmune hemolytic anemia, aplastic anemia, acute pancreatitis, mononeuritis, reactive arthritis, glomerulonephritis, cryoglobulinemia, Guillain–Barre syndrome, and pleural or pericardial effusion. A rare manifestation of hepatitis A is acute myocarditis. We report a case of a young woman who presented with “flu-like symptoms” and was found to have severe elevation of liver enzymes due to acute hepatitis A infection. On her 3rd day of admission, the patient developed chest pain and nonspecific electrocardiographic changes. Her troponins rose to 16.4  ng/mL, and a transthoracic echocardiogram revealed global hypokinesis and a depressed ejection fraction at 30%. A CT angiography showed no evidence of significant coronary artery disease. The patient was managed supportively, and symptoms and laboratory findings slowly improved over the next 7 days. Her chest pain resolved and a follow-up echocardiogram showed improved ejection fraction to 45%.
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spelling doaj-art-9d66773bbd4c459899667a5256b179472025-02-03T01:31:57ZengWileyCase Reports in Medicine1687-96271687-96352018-01-01201810.1155/2018/36251393625139A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature ReviewOlivia Allen0Ahmed Edhi1Adam Hafeez2Alexandra Halalau3Internal Medicine Department, Beaumont Hospital, Royal Oak, MI, USAInternal Medicine Department, Beaumont Hospital, Royal Oak, MI, USAInternal Medicine Department, Beaumont Hospital, Royal Oak, MI, USAInternal Medicine Department, Beaumont Hospital, Royal Oak, MI, USAHepatitis A is a common viral infection with a benign course but in rare cases can progress to acute liver failure. It usually presents with abdominal pain, nausea, vomiting, diarrhea, jaundice, anorexia, or asymptomatically, but it can also present atypically with relapsing hepatitis and prolonged cholestasis. In addition, extrahepatic manifestations have been reported, including urticarial and maculopapular rash, acute kidney injury, autoimmune hemolytic anemia, aplastic anemia, acute pancreatitis, mononeuritis, reactive arthritis, glomerulonephritis, cryoglobulinemia, Guillain–Barre syndrome, and pleural or pericardial effusion. A rare manifestation of hepatitis A is acute myocarditis. We report a case of a young woman who presented with “flu-like symptoms” and was found to have severe elevation of liver enzymes due to acute hepatitis A infection. On her 3rd day of admission, the patient developed chest pain and nonspecific electrocardiographic changes. Her troponins rose to 16.4  ng/mL, and a transthoracic echocardiogram revealed global hypokinesis and a depressed ejection fraction at 30%. A CT angiography showed no evidence of significant coronary artery disease. The patient was managed supportively, and symptoms and laboratory findings slowly improved over the next 7 days. Her chest pain resolved and a follow-up echocardiogram showed improved ejection fraction to 45%.http://dx.doi.org/10.1155/2018/3625139
spellingShingle Olivia Allen
Ahmed Edhi
Adam Hafeez
Alexandra Halalau
A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
Case Reports in Medicine
title A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
title_full A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
title_fullStr A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
title_full_unstemmed A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
title_short A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
title_sort very rare complication of hepatitis a infection acute myocarditis a case report with literature review
url http://dx.doi.org/10.1155/2018/3625139
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