Urinary kynurenine,tryptophan, and neopterin concentrations during physiological pregnancy

Urinary kynurenine,tryptophan, and neopterin concentrations during physiological pregnancy

Abstract During pregnancy the alterations of kynurenine and tryptophan metabolism play an important role in local signalling and the prevention of fetal rejection. The aim was to investigate urinary levels of kynurenine and tryptophan during physiological pregnancy, and to determine their stability...

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Main Authors: Lenka Kujovská Krčmová, Kateřina Matoušová, Lenka Javorská, Kristýna Mrštná, Nikola Přívratská, Chaweewan Suwanvecho, Dorota Turoňová, Mohamed Farrag, Marian Kacerovský, Bohuslav Melichar
Format: Article
Language:English
Published: Nature Portfolio 2025-06-01
Series:Scientific Reports
Subjects:
Urinary kynurenine
Urinary tryptophan
Healthy pregnancy
Stability study
HPLC-MS/MS
Online Access:https://doi.org/10.1038/s41598-025-04642-9
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