Risk and Surveillance of Cancers in Primary Biliary Tract Disease
Primary biliary diseases have been associated in several studies with various malignancies. Understanding the risk and optimizing surveillance strategy of these malignancies in this specific subset of patients are an important facet of clinical care. For instance, primary sclerosing cholangitis is a...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2016/3432640 |
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| _version_ | 1850171370270359552 |
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| author | Valery Hrad Yoftahe Abebe Syed Haris Ali Jared Velgersdyk Mohammed Al Hallak Mohamad Imam |
| author_facet | Valery Hrad Yoftahe Abebe Syed Haris Ali Jared Velgersdyk Mohammed Al Hallak Mohamad Imam |
| author_sort | Valery Hrad |
| collection | DOAJ |
| description | Primary biliary diseases have been associated in several studies with various malignancies. Understanding the risk and optimizing surveillance strategy of these malignancies in this specific subset of patients are an important facet of clinical care. For instance, primary sclerosing cholangitis is associated with an increased risk for cholangiocarcinoma (which is very challenging to diagnose) and when IBD is present for colorectal cancer. On the other hand, primary biliary cirrhosis patients with cirrhosis or not responding to 12 months of ursodeoxycholic acid therapy are at increased risk of hepatocellular carcinoma. In this review we will discuss in detail the risks and optimal surveillance strategies for patients with primary biliary diseases. |
| format | Article |
| id | doaj-art-9d600dc4b42049b9b99aa83ce2da1f12 |
| institution | OA Journals |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-9d600dc4b42049b9b99aa83ce2da1f122025-08-20T02:20:17ZengWileyGastroenterology Research and Practice1687-61211687-630X2016-01-01201610.1155/2016/34326403432640Risk and Surveillance of Cancers in Primary Biliary Tract DiseaseValery Hrad0Yoftahe Abebe1Syed Haris Ali2Jared Velgersdyk3Mohammed Al Hallak4Mohamad Imam5Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USADepartment of Internal Medicine, University of North Dakota, Fargo, ND 58102, USADepartment of Internal Medicine, University of North Dakota, Fargo, ND 58102, USADepartment of Internal Medicine, University of North Dakota, Fargo, ND 58102, USADepartment of General Internal Medicine, MD Anderson Cancer Center, Houston, TX 77030, USADepartment of Internal Medicine, University of North Dakota, Fargo, ND 58102, USAPrimary biliary diseases have been associated in several studies with various malignancies. Understanding the risk and optimizing surveillance strategy of these malignancies in this specific subset of patients are an important facet of clinical care. For instance, primary sclerosing cholangitis is associated with an increased risk for cholangiocarcinoma (which is very challenging to diagnose) and when IBD is present for colorectal cancer. On the other hand, primary biliary cirrhosis patients with cirrhosis or not responding to 12 months of ursodeoxycholic acid therapy are at increased risk of hepatocellular carcinoma. In this review we will discuss in detail the risks and optimal surveillance strategies for patients with primary biliary diseases.http://dx.doi.org/10.1155/2016/3432640 |
| spellingShingle | Valery Hrad Yoftahe Abebe Syed Haris Ali Jared Velgersdyk Mohammed Al Hallak Mohamad Imam Risk and Surveillance of Cancers in Primary Biliary Tract Disease Gastroenterology Research and Practice |
| title | Risk and Surveillance of Cancers in Primary Biliary Tract Disease |
| title_full | Risk and Surveillance of Cancers in Primary Biliary Tract Disease |
| title_fullStr | Risk and Surveillance of Cancers in Primary Biliary Tract Disease |
| title_full_unstemmed | Risk and Surveillance of Cancers in Primary Biliary Tract Disease |
| title_short | Risk and Surveillance of Cancers in Primary Biliary Tract Disease |
| title_sort | risk and surveillance of cancers in primary biliary tract disease |
| url | http://dx.doi.org/10.1155/2016/3432640 |
| work_keys_str_mv | AT valeryhrad riskandsurveillanceofcancersinprimarybiliarytractdisease AT yoftaheabebe riskandsurveillanceofcancersinprimarybiliarytractdisease AT syedharisali riskandsurveillanceofcancersinprimarybiliarytractdisease AT jaredvelgersdyk riskandsurveillanceofcancersinprimarybiliarytractdisease AT mohammedalhallak riskandsurveillanceofcancersinprimarybiliarytractdisease AT mohamadimam riskandsurveillanceofcancersinprimarybiliarytractdisease |