Long term oncologic surveillance in Maffucci syndrome: A case report

Maffucci syndrome is a rare disorder of bone and soft tissue characterized by multiple enchondromas and hemangiomas. Patients with this disorder are at significantly increased risk for malignant transformation of the lesions; of particular note are chondrosarcomas, gliomas, ovarian tumors and other...

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Main Author: Michael E. McGarry
Format: Article
Language:English
Published: Galenos Publishing House 2017-12-01
Series:Journal of Oncological Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452336417300596
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author Michael E. McGarry
author_facet Michael E. McGarry
author_sort Michael E. McGarry
collection DOAJ
description Maffucci syndrome is a rare disorder of bone and soft tissue characterized by multiple enchondromas and hemangiomas. Patients with this disorder are at significantly increased risk for malignant transformation of the lesions; of particular note are chondrosarcomas, gliomas, ovarian tumors and other sarcomas. Additionally, patients are affected by skeletal malformations including limb length discrepancies and deformities of the hands, feet and upper and lower limbs. Because of the rarity of the condition, there is currently no consensus for long-term screening of these patients. We suggest a regimen including annual surveillance using advanced imaging and routine physical examination.
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institution Kabale University
issn 2452-3364
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spelling doaj-art-9d4a2018ec7d491e8e704b80a1eebcd62025-08-20T03:57:03ZengGalenos Publishing HouseJournal of Oncological Sciences2452-33642017-12-013314014410.1016/j.jons.2017.08.003Long term oncologic surveillance in Maffucci syndrome: A case reportMichael E. McGarry0Division of Sports Medicine (SMART), CAPT James A. Lovell Federal Health Care Center, North Chicago, IL, USAMaffucci syndrome is a rare disorder of bone and soft tissue characterized by multiple enchondromas and hemangiomas. Patients with this disorder are at significantly increased risk for malignant transformation of the lesions; of particular note are chondrosarcomas, gliomas, ovarian tumors and other sarcomas. Additionally, patients are affected by skeletal malformations including limb length discrepancies and deformities of the hands, feet and upper and lower limbs. Because of the rarity of the condition, there is currently no consensus for long-term screening of these patients. We suggest a regimen including annual surveillance using advanced imaging and routine physical examination.http://www.sciencedirect.com/science/article/pii/S2452336417300596EnchondromaMaffucciVascular malformationSarcomaGlioma
spellingShingle Michael E. McGarry
Long term oncologic surveillance in Maffucci syndrome: A case report
Journal of Oncological Sciences
Enchondroma
Maffucci
Vascular malformation
Sarcoma
Glioma
title Long term oncologic surveillance in Maffucci syndrome: A case report
title_full Long term oncologic surveillance in Maffucci syndrome: A case report
title_fullStr Long term oncologic surveillance in Maffucci syndrome: A case report
title_full_unstemmed Long term oncologic surveillance in Maffucci syndrome: A case report
title_short Long term oncologic surveillance in Maffucci syndrome: A case report
title_sort long term oncologic surveillance in maffucci syndrome a case report
topic Enchondroma
Maffucci
Vascular malformation
Sarcoma
Glioma
url http://www.sciencedirect.com/science/article/pii/S2452336417300596
work_keys_str_mv AT michaelemcgarry longtermoncologicsurveillanceinmaffuccisyndromeacasereport