Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent

Oxidative stress-induced NCC activation in the development of nocturnal polyuria in mice: Therapeutic potential of a sustained hydrogen-releasing silicon-based agent

Nocturnal polyuria is a prevalent condition associated with significant deterioration in quality of life and increased risk of mortality. Despite its clinical relevance, the underlying pathogenesis is poorly understood, and existing therapies have limited efficacy. A recent study in mouse model reve...

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Bibliographic Details
Main Authors: Yosuke Sekii, Hiroshi Kiuchi, Kentaro Takezawa, Norichika Ueda, Takahiro Imanaka, Sohei Kuribayashi, Koichi Okada, Shinichiro Fukuhara, Ryoichi Imamura, Hiromistu Negoro, Yuki Kobayashi, Hikaru Kobayashi, Norio Nonomura
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Biochemistry and Biophysics Reports
Subjects:
NCC
Nocturia
Nocturnal polyuria
Oxidative stress
Silicon
Sodium
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082500010X
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