Primary Neuroendocrine Tumor in Brain
The incidence of brain metastases for neuroendocrine tumor (NET) is reportedly 1.5~5%, and the origin is usually pulmonary. A 77-year-old man presented to our hospital with headache and disturbance of specific skilled motor activities. Computed tomography (CT) showed a massive neoplastic lesion orig...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/295253 |
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| author | Ryota Tamura Yoshiaki Kuroshima Yoshiki Nakamura |
| author_facet | Ryota Tamura Yoshiaki Kuroshima Yoshiki Nakamura |
| author_sort | Ryota Tamura |
| collection | DOAJ |
| description | The incidence of brain metastases for neuroendocrine tumor (NET) is reportedly 1.5~5%, and the origin is usually pulmonary. A 77-year-old man presented to our hospital with headache and disturbance of specific skilled motor activities. Computed tomography (CT) showed a massive neoplastic lesion originating in the left temporal and parietal lobes that caused a mass edematous effect. Grossly, total resection of the tumor was achieved. Histological examination revealed much nuclear atypia and mitotic figures. Staining for CD56, chromogranin A, and synaptophysin was positive, indicating NET. The MIB-1 index was 37%. Histopathologically, the tumor was diagnosed as NET. After surgery, gastroscopy and colonoscopy were performed, but the origin was not seen. After discharge, CT and FDG-PET (fluoro-2-deoxy-d-glucose positron emission tomography) were performed every 3 months. Two years later we have not determined the origin of the tumor. It is possible that the brain is the primary site of this NET. To our knowledge, this is the first reported case of this phenomenon. |
| format | Article |
| id | doaj-art-9d3dae87911a466eb49e3610dc98ae06 |
| institution | Kabale University |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-9d3dae87911a466eb49e3610dc98ae062025-02-03T05:50:25ZengWileyCase Reports in Neurological Medicine2090-66682090-66762014-01-01201410.1155/2014/295253295253Primary Neuroendocrine Tumor in BrainRyota Tamura0Yoshiaki Kuroshima1Yoshiki Nakamura2Department of Neurosurgery, Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, JapanDepartment of Neurosurgery, Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, JapanDepartment of Neurosurgery, Tokyo Medical Center, 2-5-1 Higashigaoka, Meguro-ku, Tokyo 152-8902, JapanThe incidence of brain metastases for neuroendocrine tumor (NET) is reportedly 1.5~5%, and the origin is usually pulmonary. A 77-year-old man presented to our hospital with headache and disturbance of specific skilled motor activities. Computed tomography (CT) showed a massive neoplastic lesion originating in the left temporal and parietal lobes that caused a mass edematous effect. Grossly, total resection of the tumor was achieved. Histological examination revealed much nuclear atypia and mitotic figures. Staining for CD56, chromogranin A, and synaptophysin was positive, indicating NET. The MIB-1 index was 37%. Histopathologically, the tumor was diagnosed as NET. After surgery, gastroscopy and colonoscopy were performed, but the origin was not seen. After discharge, CT and FDG-PET (fluoro-2-deoxy-d-glucose positron emission tomography) were performed every 3 months. Two years later we have not determined the origin of the tumor. It is possible that the brain is the primary site of this NET. To our knowledge, this is the first reported case of this phenomenon.http://dx.doi.org/10.1155/2014/295253 |
| spellingShingle | Ryota Tamura Yoshiaki Kuroshima Yoshiki Nakamura Primary Neuroendocrine Tumor in Brain Case Reports in Neurological Medicine |
| title | Primary Neuroendocrine Tumor in Brain |
| title_full | Primary Neuroendocrine Tumor in Brain |
| title_fullStr | Primary Neuroendocrine Tumor in Brain |
| title_full_unstemmed | Primary Neuroendocrine Tumor in Brain |
| title_short | Primary Neuroendocrine Tumor in Brain |
| title_sort | primary neuroendocrine tumor in brain |
| url | http://dx.doi.org/10.1155/2014/295253 |
| work_keys_str_mv | AT ryotatamura primaryneuroendocrinetumorinbrain AT yoshiakikuroshima primaryneuroendocrinetumorinbrain AT yoshikinakamura primaryneuroendocrinetumorinbrain |