Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease
Multicentric Castleman disease (MCD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of MCD has not been clarified to date. The coexistence of MCD with chronic myelo...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2018/5895903 |
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| author | Feng Li Xiaomei Zhang Yanting Guo Yuandong Zhu Yicun Wu Yun Ling |
| author_facet | Feng Li Xiaomei Zhang Yanting Guo Yuandong Zhu Yicun Wu Yun Ling |
| author_sort | Feng Li |
| collection | DOAJ |
| description | Multicentric Castleman disease (MCD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of MCD has not been clarified to date. The coexistence of MCD with chronic myelomonocytic leukemia (CMML) has been rarely reported. Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. Herein, we report on one case of MCD coexisting with CMML and elucidate the underlying mechanism of pathology in some aspects. |
| format | Article |
| id | doaj-art-9d2eebb1f2744288a6e7ebb0eac76ee0 |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-9d2eebb1f2744288a6e7ebb0eac76ee02025-02-03T01:20:15ZengWileyCase Reports in Hematology2090-65602090-65792018-01-01201810.1155/2018/58959035895903Chronic Myelomonocytic Leukemia following Multicentric Castleman DiseaseFeng Li0Xiaomei Zhang1Yanting Guo2Yuandong Zhu3Yicun Wu4Yun Ling5Department of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaDepartment of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaDepartment of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaDepartment of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaDepartment of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaDepartment of Hematology, The First People’s Hospital of Changzhou, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, ChinaMulticentric Castleman disease (MCD) is a rare nonmalignant lymphoproliferative disorder presenting systemic symptoms such as fever, night sweats, fatigue, anemia, effusions, and multifocal lymphadenopathy. The etiology of MCD has not been clarified to date. The coexistence of MCD with chronic myelomonocytic leukemia (CMML) has been rarely reported. Although the pathogenesis remains unclear, this association probably reflects an incidental and fortuitous finding rather than the alteration of a common pluripotent stem cell precursor. Herein, we report on one case of MCD coexisting with CMML and elucidate the underlying mechanism of pathology in some aspects.http://dx.doi.org/10.1155/2018/5895903 |
| spellingShingle | Feng Li Xiaomei Zhang Yanting Guo Yuandong Zhu Yicun Wu Yun Ling Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease Case Reports in Hematology |
| title | Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease |
| title_full | Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease |
| title_fullStr | Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease |
| title_full_unstemmed | Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease |
| title_short | Chronic Myelomonocytic Leukemia following Multicentric Castleman Disease |
| title_sort | chronic myelomonocytic leukemia following multicentric castleman disease |
| url | http://dx.doi.org/10.1155/2018/5895903 |
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