Quality of life after ICU: 1-year follow-up in patients with and without COVID
Abstract Background The purpose of this study was to perform a 1-year follow-up after ICU discharge and evaluate post-intensive care syndrome (PICS) in both COVID (GroupCov) and NON COVID (GroupNCov) patients. Methods All consecutive patients discharged from our Intensive Care Unit (ICU) from June t...
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BMC
2025-07-01
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| Series: | Journal of Anesthesia, Analgesia and Critical Care |
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| Online Access: | https://doi.org/10.1186/s44158-025-00253-y |
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| author | M. Rauseo G. Ferrara A. Cotoia F. Cardinale S. Padalino N. Latronico L. Mirabella G. Cinnella |
| author_facet | M. Rauseo G. Ferrara A. Cotoia F. Cardinale S. Padalino N. Latronico L. Mirabella G. Cinnella |
| author_sort | M. Rauseo |
| collection | DOAJ |
| description | Abstract Background The purpose of this study was to perform a 1-year follow-up after ICU discharge and evaluate post-intensive care syndrome (PICS) in both COVID (GroupCov) and NON COVID (GroupNCov) patients. Methods All consecutive patients discharged from our Intensive Care Unit (ICU) from June to December 2022 were prospectively screened. Scheduled in-person visits were carried on 3, 6, and 12 months after ICU discharge to evaluate physical, cognitive, and mental health status using different scale evaluations (SF-36, Barthel Index, ISI score, PCL-5 score, MNA-sf score, Fatigue Severity Score, MoCA Test, HADS and GDS) by means of standardized questionnaires. Results Eighty patients (50 GroupCov vs 30 GroupNCov) were initially included, but some patients did not attend all follow-up visits. At 1-year follow-up, 60 patients (30 COVID-19 and 30 non-COVID) completed all evaluations. Both groups showed PICS, but GroupCov had a better nutritional status, better outcomes in physical evaluations, and a better perception of Quality of Life (QoL) and mental health status, but a worse cognitive assessment in the MoCA Test. Moreover, heterogeneity analysis showed that GroupNCov patients had the same trend during follow-up, while in GroupCov different trends were observed over time, especially a worse nutritional state, often found in older patients, that was related to a longer hospital stay and worse psychophysical outcomes. Conclusions This study shows that PICS in SARS-COV2 patients is not always homogeneous, and that different clusters of psychophysical patterns may develop over time. Although our study was only observational, it seems from our preliminary results that performing a follow-up could be the basis for a secondary prevention and to develop new therapeutic strategies after patients discharge from ICU. |
| format | Article |
| id | doaj-art-9d2ad893e20446cf816f170e1a7d5c29 |
| institution | Kabale University |
| issn | 2731-3786 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Anesthesia, Analgesia and Critical Care |
| spelling | doaj-art-9d2ad893e20446cf816f170e1a7d5c292025-08-20T04:01:42ZengBMCJournal of Anesthesia, Analgesia and Critical Care2731-37862025-07-01511910.1186/s44158-025-00253-yQuality of life after ICU: 1-year follow-up in patients with and without COVIDM. Rauseo0G. Ferrara1A. Cotoia2F. Cardinale3S. Padalino4N. Latronico5L. Mirabella6G. Cinnella7Anesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaAnesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaAnesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaAnesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaOncological Molecular Biology-Clinic Hereditary Familial Tumors, University Hospital of FoggiaAnesthesia and Critical Care Medicine, Department of Medical and Surgical Specialties, Radiological Science and Public Health, University of BresciaAnesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaAnesthesia and Intensive Care Unit, Department of Medical Surgical Science, University Hospital of FoggiaAbstract Background The purpose of this study was to perform a 1-year follow-up after ICU discharge and evaluate post-intensive care syndrome (PICS) in both COVID (GroupCov) and NON COVID (GroupNCov) patients. Methods All consecutive patients discharged from our Intensive Care Unit (ICU) from June to December 2022 were prospectively screened. Scheduled in-person visits were carried on 3, 6, and 12 months after ICU discharge to evaluate physical, cognitive, and mental health status using different scale evaluations (SF-36, Barthel Index, ISI score, PCL-5 score, MNA-sf score, Fatigue Severity Score, MoCA Test, HADS and GDS) by means of standardized questionnaires. Results Eighty patients (50 GroupCov vs 30 GroupNCov) were initially included, but some patients did not attend all follow-up visits. At 1-year follow-up, 60 patients (30 COVID-19 and 30 non-COVID) completed all evaluations. Both groups showed PICS, but GroupCov had a better nutritional status, better outcomes in physical evaluations, and a better perception of Quality of Life (QoL) and mental health status, but a worse cognitive assessment in the MoCA Test. Moreover, heterogeneity analysis showed that GroupNCov patients had the same trend during follow-up, while in GroupCov different trends were observed over time, especially a worse nutritional state, often found in older patients, that was related to a longer hospital stay and worse psychophysical outcomes. Conclusions This study shows that PICS in SARS-COV2 patients is not always homogeneous, and that different clusters of psychophysical patterns may develop over time. Although our study was only observational, it seems from our preliminary results that performing a follow-up could be the basis for a secondary prevention and to develop new therapeutic strategies after patients discharge from ICU.https://doi.org/10.1186/s44158-025-00253-yCovid-19Follow-upPICSICU |
| spellingShingle | M. Rauseo G. Ferrara A. Cotoia F. Cardinale S. Padalino N. Latronico L. Mirabella G. Cinnella Quality of life after ICU: 1-year follow-up in patients with and without COVID Journal of Anesthesia, Analgesia and Critical Care Covid-19 Follow-up PICS ICU |
| title | Quality of life after ICU: 1-year follow-up in patients with and without COVID |
| title_full | Quality of life after ICU: 1-year follow-up in patients with and without COVID |
| title_fullStr | Quality of life after ICU: 1-year follow-up in patients with and without COVID |
| title_full_unstemmed | Quality of life after ICU: 1-year follow-up in patients with and without COVID |
| title_short | Quality of life after ICU: 1-year follow-up in patients with and without COVID |
| title_sort | quality of life after icu 1 year follow up in patients with and without covid |
| topic | Covid-19 Follow-up PICS ICU |
| url | https://doi.org/10.1186/s44158-025-00253-y |
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