Neuron-to-glia signaling drives critical period experience-dependent synapse pruning

Abstract Critical periods enable early-life synaptic connectivity optimization whereby initial sensory experience remodels circuits to a variable environment. In the Drosophila juvenile brain, synapse remodeling occurs within the precisely-mapped olfactory circuit, which has an extensively character...

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Bibliographic Details
Main Authors: Nichalas Nelson, Kendal Broadie
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-11528-3
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