Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review

Implant-related infections are one of the major challenges faced by orthopedic surgeries. Developing implants with inherent antibacterial properties is an effective strategy to address this issue. Biodegradable magnesium and magnesium alloys have become a research hotspot due to their good bioactivi...

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Main Authors: Qingfeng Song, Lingzhi Yang, Fang Yi, Chao Chen, Jing Guo, Zihua Qi, Yihan Song
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/14/11/939
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author Qingfeng Song
Lingzhi Yang
Fang Yi
Chao Chen
Jing Guo
Zihua Qi
Yihan Song
author_facet Qingfeng Song
Lingzhi Yang
Fang Yi
Chao Chen
Jing Guo
Zihua Qi
Yihan Song
author_sort Qingfeng Song
collection DOAJ
description Implant-related infections are one of the major challenges faced by orthopedic surgeries. Developing implants with inherent antibacterial properties is an effective strategy to address this issue. Biodegradable magnesium and magnesium alloys have become a research hotspot due to their good bioactivity, mechanical properties, biocompatibility, and excellent antibacterial ability. However, magnesium and its alloys have rapid corrosion, and the difficulty in expelling harmful magnesium ions and hydrogen gas produced by degradation from the body. This review summarizes the mainstream surface modification techniques such as laser surface modification, friction stir processing, and micro-arc oxidation, along with their impact on the antimicrobial properties of magnesium-based materials. This paper reviews the latest research progress on improving the antibacterial properties of magnesium alloys through alloying and introduces the antibacterial effects of mainstream magnesium alloys and also elaborates on the antibacterial mechanism of magnesium alloy materials. It is expected to provide more basis and insights for the design of biodegradable magnesium alloys with antibacterial properties, thereby promoting their development and clinical application.
format Article
id doaj-art-9d1e68f0dce648579af4f7badb642ff9
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issn 2073-4352
language English
publishDate 2024-10-01
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record_format Article
series Crystals
spelling doaj-art-9d1e68f0dce648579af4f7badb642ff92025-08-20T01:53:44ZengMDPI AGCrystals2073-43522024-10-01141193910.3390/cryst14110939Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A ReviewQingfeng Song0Lingzhi Yang1Fang Yi2Chao Chen3Jing Guo4Zihua Qi5Yihan Song6School of Minerals Processing and Bioengineering, Central South University, Changsha 410083, ChinaSchool of Minerals Processing and Bioengineering, Central South University, Changsha 410083, ChinaXiangya School of Stomatology, Central South University, Changsha 410008, ChinaCollege of Materials Science and Engineering, Taiyuan University of Technology, Taiyuan 030024, ChinaXiangya School of Stomatology, Central South University, Changsha 410008, ChinaXiangya School of Stomatology, Central South University, Changsha 410008, ChinaXiangya School of Stomatology, Central South University, Changsha 410008, ChinaImplant-related infections are one of the major challenges faced by orthopedic surgeries. Developing implants with inherent antibacterial properties is an effective strategy to address this issue. Biodegradable magnesium and magnesium alloys have become a research hotspot due to their good bioactivity, mechanical properties, biocompatibility, and excellent antibacterial ability. However, magnesium and its alloys have rapid corrosion, and the difficulty in expelling harmful magnesium ions and hydrogen gas produced by degradation from the body. This review summarizes the mainstream surface modification techniques such as laser surface modification, friction stir processing, and micro-arc oxidation, along with their impact on the antimicrobial properties of magnesium-based materials. This paper reviews the latest research progress on improving the antibacterial properties of magnesium alloys through alloying and introduces the antibacterial effects of mainstream magnesium alloys and also elaborates on the antibacterial mechanism of magnesium alloy materials. It is expected to provide more basis and insights for the design of biodegradable magnesium alloys with antibacterial properties, thereby promoting their development and clinical application.https://www.mdpi.com/2073-4352/14/11/939antibacterial propertymagnesium alloysbiodegradable magnesium materialsurface modificationsbiomedical implants
spellingShingle Qingfeng Song
Lingzhi Yang
Fang Yi
Chao Chen
Jing Guo
Zihua Qi
Yihan Song
Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
Crystals
antibacterial property
magnesium alloys
biodegradable magnesium material
surface modifications
biomedical implants
title Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
title_full Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
title_fullStr Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
title_full_unstemmed Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
title_short Antibacterial Pure Magnesium and Magnesium Alloys for Biomedical Materials—A Review
title_sort antibacterial pure magnesium and magnesium alloys for biomedical materials a review
topic antibacterial property
magnesium alloys
biodegradable magnesium material
surface modifications
biomedical implants
url https://www.mdpi.com/2073-4352/14/11/939
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AT lingzhiyang antibacterialpuremagnesiumandmagnesiumalloysforbiomedicalmaterialsareview
AT fangyi antibacterialpuremagnesiumandmagnesiumalloysforbiomedicalmaterialsareview
AT chaochen antibacterialpuremagnesiumandmagnesiumalloysforbiomedicalmaterialsareview
AT jingguo antibacterialpuremagnesiumandmagnesiumalloysforbiomedicalmaterialsareview
AT zihuaqi antibacterialpuremagnesiumandmagnesiumalloysforbiomedicalmaterialsareview
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