Slow-wave sleep is associated with nucleus accumbens volume in elderly adults
Slow-wave sleep (SWS) is essential for restorative neural processes and its decline is associated with both healthy and pathological ageing. Building on previous rodent research, this longitudinal study identified a significant association between nucleus accumbens (NAcc) volume and SWS duration in...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-04-01
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| Series: | NeuroImage |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1053811925001752 |
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| author | Kitti Bán Ádám Nárai Noémi Báthori Éva M. Bankó Adél Bihari Vivien Tomacsek Tibor Kovács Béla Weiss Petra Hermann Péter Simor Zoltán Vidnyánszky |
| author_facet | Kitti Bán Ádám Nárai Noémi Báthori Éva M. Bankó Adél Bihari Vivien Tomacsek Tibor Kovács Béla Weiss Petra Hermann Péter Simor Zoltán Vidnyánszky |
| author_sort | Kitti Bán |
| collection | DOAJ |
| description | Slow-wave sleep (SWS) is essential for restorative neural processes and its decline is associated with both healthy and pathological ageing. Building on previous rodent research, this longitudinal study identified a significant association between nucleus accumbens (NAcc) volume and SWS duration in cognitively unimpaired older adults, whilst no significant link was observed between NAcc volume and N2 or rapid eye movement (REM) sleep percentage. Our findings support the involvement of the NAcc in ageing-related modulation of SWS and thus suggest the NAcc as a potential neural marker or therapeutic target for improving SWS. |
| format | Article |
| id | doaj-art-9d1da82d0f3c428eabf6cb7e5c1d4a9c |
| institution | OA Journals |
| issn | 1095-9572 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage |
| spelling | doaj-art-9d1da82d0f3c428eabf6cb7e5c1d4a9c2025-08-20T02:25:45ZengElsevierNeuroImage1095-95722025-04-0131012117310.1016/j.neuroimage.2025.121173Slow-wave sleep is associated with nucleus accumbens volume in elderly adultsKitti Bán0Ádám Nárai1Noémi Báthori2Éva M. Bankó3Adél Bihari4Vivien Tomacsek5Tibor Kovács6Béla Weiss7Petra Hermann8Péter Simor9Zoltán Vidnyánszky10Brain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary; University of Glasgow, Glasgow, United Kingdom; Correspondence authors.Brain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary; Doctoral School of Biology and Sport Biology, Institute of Biology, Faculty of Sciences, University of Pécs, Pécs, HungaryDepartment of Cognitive Science, Faculty of Natural Sciences, Budapest University of Technology and Economics, Budapest, HungaryBrain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, HungaryBrain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, HungaryDoctoral School of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Institute of Psychology, ELTE Eötvös Loránd University, Budapest, HungaryDepartment of Neurology, Semmelweis University, Budapest, HungaryBrain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary; Machine Perception Research Laboratory, HUN-REN Institute for Computer Science and Control, Budapest, HungaryBrain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, HungaryInstitute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary; Institute of Behavioral Sciences, Semmelweis University, Budapest, HungaryBrain Imaging Centre, HUN-REN Research Centre for Natural Sciences, Budapest, Hungary; Correspondence authors.Slow-wave sleep (SWS) is essential for restorative neural processes and its decline is associated with both healthy and pathological ageing. Building on previous rodent research, this longitudinal study identified a significant association between nucleus accumbens (NAcc) volume and SWS duration in cognitively unimpaired older adults, whilst no significant link was observed between NAcc volume and N2 or rapid eye movement (REM) sleep percentage. Our findings support the involvement of the NAcc in ageing-related modulation of SWS and thus suggest the NAcc as a potential neural marker or therapeutic target for improving SWS.http://www.sciencedirect.com/science/article/pii/S1053811925001752Neurocognitive ageingElectroencephalographyDopaminergic systemLongitudinal study |
| spellingShingle | Kitti Bán Ádám Nárai Noémi Báthori Éva M. Bankó Adél Bihari Vivien Tomacsek Tibor Kovács Béla Weiss Petra Hermann Péter Simor Zoltán Vidnyánszky Slow-wave sleep is associated with nucleus accumbens volume in elderly adults NeuroImage Neurocognitive ageing Electroencephalography Dopaminergic system Longitudinal study |
| title | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| title_full | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| title_fullStr | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| title_full_unstemmed | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| title_short | Slow-wave sleep is associated with nucleus accumbens volume in elderly adults |
| title_sort | slow wave sleep is associated with nucleus accumbens volume in elderly adults |
| topic | Neurocognitive ageing Electroencephalography Dopaminergic system Longitudinal study |
| url | http://www.sciencedirect.com/science/article/pii/S1053811925001752 |
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