Identification of a novel PPARβ/δ/miR‐21‐3p axis in UV‐induced skin inflammation

Identification of a novel PPARβ/δ/miR‐21‐3p axis in UV‐induced skin inflammation

Abstract Although excessive exposure to UV is widely recognized as a major factor leading to skin perturbations and cancer, the complex mechanisms underlying inflammatory skin disorders resulting from UV exposure remain incompletely characterized. The nuclear hormone receptor PPARβ/δ is known to con...

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Main Authors: Gwendoline Degueurce, Ilenia D'Errico, Christine Pich, Mark Ibberson, Frédéric Schütz, Alexandra Montagner, Marie Sgandurra, Lionel Mury, Paris Jafari, Akash Boda, Julien Meunier, Roger Rezzonico, Nicolò Costantino Brembilla, Daniel Hohl, Antonios Kolios, Günther Hofbauer, Ioannis Xenarios, Liliane Michalik
Format: Article
Language:English
Published: Springer Nature 2016-06-01
Series:EMBO Molecular Medicine
Subjects:
inflammation
miRNA
PPARβ/δ
skin
therapeutics
Online Access:https://doi.org/10.15252/emmm.201505384
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