Adenoid cystic carcinoma of the larynx: Case report and review of literature
Adenoid cystic carcinoma (ACC) is a rare malignant neoplasm arising in both major and minor salivary glands. It represents approximately 1% of all head and neck cancers and about 10% of salivary gland tumors. Laryngeal adenoid cystic carcinoma (LACC) is a rare entity that most frequently arises in t...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-08-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325003619 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850226179445882880 |
|---|---|
| author | Fatima Zahra Es-Sahli Achraf Amine Sbai Anass Haloui Drissia Benfadil Amal Bennani Azzedine Lachkar Adil ABDNBI Tsen Fahd El Ayoubi |
| author_facet | Fatima Zahra Es-Sahli Achraf Amine Sbai Anass Haloui Drissia Benfadil Amal Bennani Azzedine Lachkar Adil ABDNBI Tsen Fahd El Ayoubi |
| author_sort | Fatima Zahra Es-Sahli |
| collection | DOAJ |
| description | Adenoid cystic carcinoma (ACC) is a rare malignant neoplasm arising in both major and minor salivary glands. It represents approximately 1% of all head and neck cancers and about 10% of salivary gland tumors. Laryngeal adenoid cystic carcinoma (LACC) is a rare entity that most frequently arises in the subglottic region. It is characterized by slow progression, perineuronal invasion, frequent local recurrences and delayed distant metastasis. Surgical resection remains the gold standard for the treatment of ACC; however, the role of adjuvant radiotherapy and prophylactic neck dissection remains uncertain and is widely debated in the literature.This case report describes a 60-year-old male patient who presented with progressive dysphagia and worsening dyspnea. Clinical evaluation, including computed tomography (CT), revealed a lesion involving the left glottic and supraglottic regions. Biopsy obtained via direct laryngoscopy confirmed the diagnosis of laryngeal adenoid cystic carcinoma (LACC). The patient subsequently underwent total laryngectomy with adjuvant radiotherapy. |
| format | Article |
| id | doaj-art-9d196b08a0be4e8fa27f434af0e82dff |
| institution | OA Journals |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-9d196b08a0be4e8fa27f434af0e82dff2025-08-20T02:05:09ZengElsevierRadiology Case Reports1930-04332025-08-012083710371410.1016/j.radcr.2025.04.071Adenoid cystic carcinoma of the larynx: Case report and review of literatureFatima Zahra Es-Sahli0Achraf Amine Sbai1Anass Haloui2Drissia Benfadil3Amal Bennani4Azzedine Lachkar5Adil ABDNBI Tsen6Fahd El Ayoubi7Department of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco; Corresponding authors.Department of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco; Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, Morocco; Corresponding authors.Laboratory of Pathological Anatomy, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, MoroccoDepartment of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco; Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, MoroccoLaboratory of Pathological Anatomy, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, MoroccoDepartment of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco; Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, MoroccoLaboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, Morocco; Department of Maxillofacial Surgery, Mohammed VI University Hospital, Oujda, MoroccoDepartment of Ear Nose and Throat, Mohammed VI University Hospital, Oujda, Morocco; Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, Mohammed the First University, Oujda, MoroccoAdenoid cystic carcinoma (ACC) is a rare malignant neoplasm arising in both major and minor salivary glands. It represents approximately 1% of all head and neck cancers and about 10% of salivary gland tumors. Laryngeal adenoid cystic carcinoma (LACC) is a rare entity that most frequently arises in the subglottic region. It is characterized by slow progression, perineuronal invasion, frequent local recurrences and delayed distant metastasis. Surgical resection remains the gold standard for the treatment of ACC; however, the role of adjuvant radiotherapy and prophylactic neck dissection remains uncertain and is widely debated in the literature.This case report describes a 60-year-old male patient who presented with progressive dysphagia and worsening dyspnea. Clinical evaluation, including computed tomography (CT), revealed a lesion involving the left glottic and supraglottic regions. Biopsy obtained via direct laryngoscopy confirmed the diagnosis of laryngeal adenoid cystic carcinoma (LACC). The patient subsequently underwent total laryngectomy with adjuvant radiotherapy.http://www.sciencedirect.com/science/article/pii/S1930043325003619Adenoid cystic carcinomaPerineuronal invasionSubglottic areaDyspneaLaryngectomyNeck dissection |
| spellingShingle | Fatima Zahra Es-Sahli Achraf Amine Sbai Anass Haloui Drissia Benfadil Amal Bennani Azzedine Lachkar Adil ABDNBI Tsen Fahd El Ayoubi Adenoid cystic carcinoma of the larynx: Case report and review of literature Radiology Case Reports Adenoid cystic carcinoma Perineuronal invasion Subglottic area Dyspnea Laryngectomy Neck dissection |
| title | Adenoid cystic carcinoma of the larynx: Case report and review of literature |
| title_full | Adenoid cystic carcinoma of the larynx: Case report and review of literature |
| title_fullStr | Adenoid cystic carcinoma of the larynx: Case report and review of literature |
| title_full_unstemmed | Adenoid cystic carcinoma of the larynx: Case report and review of literature |
| title_short | Adenoid cystic carcinoma of the larynx: Case report and review of literature |
| title_sort | adenoid cystic carcinoma of the larynx case report and review of literature |
| topic | Adenoid cystic carcinoma Perineuronal invasion Subglottic area Dyspnea Laryngectomy Neck dissection |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325003619 |
| work_keys_str_mv | AT fatimazahraessahli adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT achrafaminesbai adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT anasshaloui adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT drissiabenfadil adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT amalbennani adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT azzedinelachkar adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT adilabdnbitsen adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature AT fahdelayoubi adenoidcysticcarcinomaofthelarynxcasereportandreviewofliterature |