Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review
Background: Poisoning by household cleaning products(HCPs) is common in children. Some HCPs are toxic and may cause severe complications. We assessed HCP poisonings treated in a pediatric emergency department(PED). Methods: This was a retrospective study of patients aged under 18 years with HCP pois...
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Elsevier
2021-11-01
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| Series: | Pediatrics and Neonatology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1875957221001248 |
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| author | Chen-Wei Yen En-Pei Lee Shu-Chuan Cheng Shao-Hsuan Hsia Jing-Long Huang Jung Lee |
| author_facet | Chen-Wei Yen En-Pei Lee Shu-Chuan Cheng Shao-Hsuan Hsia Jing-Long Huang Jung Lee |
| author_sort | Chen-Wei Yen |
| collection | DOAJ |
| description | Background: Poisoning by household cleaning products(HCPs) is common in children. Some HCPs are toxic and may cause severe complications. We assessed HCP poisonings treated in a pediatric emergency department(PED). Methods: This was a retrospective study of patients aged under 18 years with HCP poisoning admitted to the largest PED in Taiwan from 2011 to 2020 were recruited. Results: The records over a 10-year period from 103 children admitted to the PED because of HCP poisoning(70 boys [68%] and 33 girls [32%]), mean age 3.54 years(standard deviation [SD] = 3.15 years) were evaluated. Most poisonings were unintentional(99%, n = 102) and occurred at home(96%, n = 99). The HCPs included alkaline(74%, n = 76), acidic(25%, n = 26), and neutral(1%, n = 1) agents. Most were orally ingested(86%, n = 89). Panendoscopy was performed in 25 patients(24%), and the endoscopic(Zargar) grade was used to determine the severity of injury. Medications(steroids [9%, n = 9], antibiotics [10%, n = 10], or antacids [30%, n = 23]) were prescribed. Alkaline HCP ingestion induced severe esophageal injury(p = 0.04) and esophageal stricture(p = 0.04). Five patients(5%) exhibited esophageal strictures and required balloon dilation. On multivariate analysis, alkaline HCP ingestion(p = 0.04), severe esophageal caustic injury(Zargar grade ≥ 3) (p < 0.001), and medications(steroids [p < 0.001], antibiotics [p < 0.001], and antacids [p = 0.001]) were associated with esophageal stricture. Conclusion: Alkaline HCP ingestion and severe esophageal caustic injury(Zargar grade ≥ 3) were associated with esophageal stricture. Physicians tended to prescribe medications(steroids, antibiotics, or antacids) for patients with severe esophageal injuries to reduce the risk of esophageal stricture. The usefulness of these medications requires further study. |
| format | Article |
| id | doaj-art-9d15cdc74f03475bbb4f6beed381a268 |
| institution | OA Journals |
| issn | 1875-9572 |
| language | English |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Pediatrics and Neonatology |
| spelling | doaj-art-9d15cdc74f03475bbb4f6beed381a2682025-08-20T01:51:28ZengElsevierPediatrics and Neonatology1875-95722021-11-0162663864610.1016/j.pedneo.2021.05.026Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature reviewChen-Wei Yen0En-Pei Lee1Shu-Chuan Cheng2Shao-Hsuan Hsia3Jing-Long Huang4Jung Lee5Division of Nephrology, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, TaiwanDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, TaiwanDepartment of Family Medicine, China Medical University Hospital, Taipei, TaiwanDivision of Pediatric Critical Care Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, TaiwanDivision of Pediatric Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, TaiwanDivision of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan, Taiwan; Corresponding author. Division of Pediatric General Medicine, Department of Pediatrics, Chang Gung Memorial Hospital, Chang Gung University, No.5, Fuxing St., Guishan Dist., Taoyuan, 333, Taiwan.Background: Poisoning by household cleaning products(HCPs) is common in children. Some HCPs are toxic and may cause severe complications. We assessed HCP poisonings treated in a pediatric emergency department(PED). Methods: This was a retrospective study of patients aged under 18 years with HCP poisoning admitted to the largest PED in Taiwan from 2011 to 2020 were recruited. Results: The records over a 10-year period from 103 children admitted to the PED because of HCP poisoning(70 boys [68%] and 33 girls [32%]), mean age 3.54 years(standard deviation [SD] = 3.15 years) were evaluated. Most poisonings were unintentional(99%, n = 102) and occurred at home(96%, n = 99). The HCPs included alkaline(74%, n = 76), acidic(25%, n = 26), and neutral(1%, n = 1) agents. Most were orally ingested(86%, n = 89). Panendoscopy was performed in 25 patients(24%), and the endoscopic(Zargar) grade was used to determine the severity of injury. Medications(steroids [9%, n = 9], antibiotics [10%, n = 10], or antacids [30%, n = 23]) were prescribed. Alkaline HCP ingestion induced severe esophageal injury(p = 0.04) and esophageal stricture(p = 0.04). Five patients(5%) exhibited esophageal strictures and required balloon dilation. On multivariate analysis, alkaline HCP ingestion(p = 0.04), severe esophageal caustic injury(Zargar grade ≥ 3) (p < 0.001), and medications(steroids [p < 0.001], antibiotics [p < 0.001], and antacids [p = 0.001]) were associated with esophageal stricture. Conclusion: Alkaline HCP ingestion and severe esophageal caustic injury(Zargar grade ≥ 3) were associated with esophageal stricture. Physicians tended to prescribe medications(steroids, antibiotics, or antacids) for patients with severe esophageal injuries to reduce the risk of esophageal stricture. The usefulness of these medications requires further study.http://www.sciencedirect.com/science/article/pii/S1875957221001248childrenhousehold cleaning product(HCP)pediatricpoisoning |
| spellingShingle | Chen-Wei Yen En-Pei Lee Shu-Chuan Cheng Shao-Hsuan Hsia Jing-Long Huang Jung Lee Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review Pediatrics and Neonatology children household cleaning product(HCP) pediatric poisoning |
| title | Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review |
| title_full | Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review |
| title_fullStr | Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review |
| title_full_unstemmed | Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review |
| title_short | Household cleaning products poisoning in a pediatric emergency center: A 10- year cross-sectional study and literature review |
| title_sort | household cleaning products poisoning in a pediatric emergency center a 10 year cross sectional study and literature review |
| topic | children household cleaning product(HCP) pediatric poisoning |
| url | http://www.sciencedirect.com/science/article/pii/S1875957221001248 |
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