EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION
Aim. To compare influence of amlodipine and bisoprolol on peripheral vascular resistance (PVR) in carotid and vertebral arteries in elderly and senile men with arterial hypertension (HT) and ischemic heart disease (IHD).Material and methods. 135 patients aged 35-90 y.o. were examined. PVR was determ...
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Столичная издательская компания
2016-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/712 |
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| author | E. D. Golovanova N. N. Silaeva D. Y. Kovalev |
| author_facet | E. D. Golovanova N. N. Silaeva D. Y. Kovalev |
| author_sort | E. D. Golovanova |
| collection | DOAJ |
| description | Aim. To compare influence of amlodipine and bisoprolol on peripheral vascular resistance (PVR) in carotid and vertebral arteries in elderly and senile men with arterial hypertension (HT) and ischemic heart disease (IHD).Material and methods. 135 patients aged 35-90 y.o. were examined. PVR was determined by Doppler ultrasound in common (CCA) and internal (ICA) carotid arteries as well as vertebral artery (VA). Vascular remodeling was evaluated by volume sphygmography. The influence of the monotherapy with amlodipine or bisoprolol (2,5-5 mg once daily) on PVR in 54 patients of elderly and senile age with isolated systolic HT 1-2 degrees and IHD.Results. Therapy with amlodipine decreased of peripheral resistance of CCA, ICA in elderly and senile men with isolated systolic HT 1-2 stages and IHD. Monotherapy with bisoprolol did not increase in PVR of CCA, ICA.Conclusion. Amlodipine is effective antihypertensive drug with positive influence on pathogenetic mechanism of isolated systolic HT in elderly and senile patients. |
| format | Article |
| id | doaj-art-9d0d84d067ae42feb9f64dc64c2ad145 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-9d0d84d067ae42feb9f64dc64c2ad1452025-08-23T10:00:22ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532016-01-0155293410.20996/1819-6446-2009-5-5-29-34711EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSIONE. D. Golovanova0N. N. Silaeva1D. Y. Kovalev2Smolensk State Medical AcademySmolensk State Medical AcademySmolensk State Medical AcademyAim. To compare influence of amlodipine and bisoprolol on peripheral vascular resistance (PVR) in carotid and vertebral arteries in elderly and senile men with arterial hypertension (HT) and ischemic heart disease (IHD).Material and methods. 135 patients aged 35-90 y.o. were examined. PVR was determined by Doppler ultrasound in common (CCA) and internal (ICA) carotid arteries as well as vertebral artery (VA). Vascular remodeling was evaluated by volume sphygmography. The influence of the monotherapy with amlodipine or bisoprolol (2,5-5 mg once daily) on PVR in 54 patients of elderly and senile age with isolated systolic HT 1-2 degrees and IHD.Results. Therapy with amlodipine decreased of peripheral resistance of CCA, ICA in elderly and senile men with isolated systolic HT 1-2 stages and IHD. Monotherapy with bisoprolol did not increase in PVR of CCA, ICA.Conclusion. Amlodipine is effective antihypertensive drug with positive influence on pathogenetic mechanism of isolated systolic HT in elderly and senile patients.https://www.rpcardio.online/jour/article/view/712amlodipinebisoprololperipheral vascular resistancearterial hypertension |
| spellingShingle | E. D. Golovanova N. N. Silaeva D. Y. Kovalev EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION Рациональная фармакотерапия в кардиологии amlodipine bisoprolol peripheral vascular resistance arterial hypertension |
| title | EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION |
| title_full | EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION |
| title_fullStr | EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION |
| title_full_unstemmed | EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION |
| title_short | EFFECTS OF AMLODIPINE AND BISOPROLOL ON CAROTID AND VERTEBRAL BLOOD FLOW IN PATIENTS WITH ARTERIAL HYPERTENSION |
| title_sort | effects of amlodipine and bisoprolol on carotid and vertebral blood flow in patients with arterial hypertension |
| topic | amlodipine bisoprolol peripheral vascular resistance arterial hypertension |
| url | https://www.rpcardio.online/jour/article/view/712 |
| work_keys_str_mv | AT edgolovanova effectsofamlodipineandbisoprololoncarotidandvertebralbloodflowinpatientswitharterialhypertension AT nnsilaeva effectsofamlodipineandbisoprololoncarotidandvertebralbloodflowinpatientswitharterialhypertension AT dykovalev effectsofamlodipineandbisoprololoncarotidandvertebralbloodflowinpatientswitharterialhypertension |