2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications
Recent advances in the synthesis of functional nanomaterials and precisely engineered nanostructures have opened up new avenues for the fabrication of viable biosensors for field analysis. Two-dimensional (2D) nanomaterials provide unique hierarchical structures, high surface area, and layered confi...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Biosensors and Bioelectronics: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590137025000421 |
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| author | Desmond Lutomia Renu Poria Deepak Kala Preeti Garg Rupak Nagraik Ankur Kaushal Shagun Gupta Deepak Kumar |
| author_facet | Desmond Lutomia Renu Poria Deepak Kala Preeti Garg Rupak Nagraik Ankur Kaushal Shagun Gupta Deepak Kumar |
| author_sort | Desmond Lutomia |
| collection | DOAJ |
| description | Recent advances in the synthesis of functional nanomaterials and precisely engineered nanostructures have opened up new avenues for the fabrication of viable biosensors for field analysis. Two-dimensional (2D) nanomaterials provide unique hierarchical structures, high surface area, and layered configurations with multiple length scales and porosity, and the possibility to create functionalities for targeted recognition at their surface. In addition to providing extra features like structural color, ordered morphological features, and the capacity to detect and react to external stimuli, such hierarchical structures provide opportunities to tune the characteristics of materials. Combining these distinctive qualities of the various nanostructure types and using them as a foundation for bimolecular assemblies can yield biosensing platforms with enhanced robustness, sensitivity, and selectivity for the detection of a wide range of analytes, as well as targeted recognition and transduction properties that can have a positive impact on numerous fields. This review describes the classification, synthesis and characterization of 2D nanomaterials and their functionalization. In addition, the merits of the 2D nanomaterials and their applications in health, environmental monitoring and food safety and control are covered. The final part anticipates the advancement of 2D nanomaterials in biosensors, challenges and future directions of 2D nanomaterials in biosensors. |
| format | Article |
| id | doaj-art-9d04fc70320042faa651972e71d5e37a |
| institution | DOAJ |
| issn | 2590-1370 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Biosensors and Bioelectronics: X |
| spelling | doaj-art-9d04fc70320042faa651972e71d5e37a2025-08-20T02:55:56ZengElsevierBiosensors and Bioelectronics: X2590-13702025-08-012410061510.1016/j.biosx.2025.1006152D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applicationsDesmond Lutomia0Renu Poria1Deepak Kala2Preeti Garg3Rupak Nagraik4Ankur Kaushal5Shagun Gupta6Deepak Kumar7Department of Bio-sciences and Technology, Maharishi Markandeshwar (Deemed to Be) University, Mullana, Ambala, 134003, IndiaDepartment of Bio-sciences and Technology, Maharishi Markandeshwar (Deemed to Be) University, Mullana, Ambala, 134003, IndiaNL-11 CenteraTetrahertz Laboratory, Institute of High Pressure Physics, Polish Academy of Sciences, 29/37 Sokolowska Street, 01142, Warsaw, PolandDepartment of Oral Medicine and Radiology, Maharishi Markandeshwar College of Dental, Sciences and Research, Mullana, Ambala, 134003, IndiaDepartment of Biotechnology, Graphic Era (Deemed to be University), Dehradun, Uttarakhand, 248002, IndiaDepartment of Bio-sciences and Technology, Maharishi Markandeshwar (Deemed to Be) University, Mullana, Ambala, 134003, India; Corresponding author.Department of Bio-sciences and Technology, Maharishi Markandeshwar (Deemed to Be) University, Mullana, Ambala, 134003, India; Corresponding author.Department of Pharmaceutical Chemistry, School of Pharmaceutical Sciences, Shoolini University, Solan, Himachal Pradesh, 173 229, India; Corresponding author.Recent advances in the synthesis of functional nanomaterials and precisely engineered nanostructures have opened up new avenues for the fabrication of viable biosensors for field analysis. Two-dimensional (2D) nanomaterials provide unique hierarchical structures, high surface area, and layered configurations with multiple length scales and porosity, and the possibility to create functionalities for targeted recognition at their surface. In addition to providing extra features like structural color, ordered morphological features, and the capacity to detect and react to external stimuli, such hierarchical structures provide opportunities to tune the characteristics of materials. Combining these distinctive qualities of the various nanostructure types and using them as a foundation for bimolecular assemblies can yield biosensing platforms with enhanced robustness, sensitivity, and selectivity for the detection of a wide range of analytes, as well as targeted recognition and transduction properties that can have a positive impact on numerous fields. This review describes the classification, synthesis and characterization of 2D nanomaterials and their functionalization. In addition, the merits of the 2D nanomaterials and their applications in health, environmental monitoring and food safety and control are covered. The final part anticipates the advancement of 2D nanomaterials in biosensors, challenges and future directions of 2D nanomaterials in biosensors.http://www.sciencedirect.com/science/article/pii/S2590137025000421NanocompositesCharacterizationBiosensor2D nanomaterialsFabricationNanotechnology |
| spellingShingle | Desmond Lutomia Renu Poria Deepak Kala Preeti Garg Rupak Nagraik Ankur Kaushal Shagun Gupta Deepak Kumar 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications Biosensors and Bioelectronics: X Nanocomposites Characterization Biosensor 2D nanomaterials Fabrication Nanotechnology |
| title | 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications |
| title_full | 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications |
| title_fullStr | 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications |
| title_full_unstemmed | 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications |
| title_short | 2D nanomaterials in biosensing: Synthesis, characterization, integration in biosensors and their applications |
| title_sort | 2d nanomaterials in biosensing synthesis characterization integration in biosensors and their applications |
| topic | Nanocomposites Characterization Biosensor 2D nanomaterials Fabrication Nanotechnology |
| url | http://www.sciencedirect.com/science/article/pii/S2590137025000421 |
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