Integration of transcriptome and immunophenotyping data highlights differences in the pathogenetic kinetics of B cells across immune-mediated disease

Integration of transcriptome and immunophenotyping data highlights differences in the pathogenetic kinetics of B cells across immune-mediated disease

Objective To elucidate crucial immune cell subsets and associated immunological pathways by stratifying patients with immune-mediated diseases (IMDs) using immunophenotyping and transcriptomic approaches.Methods We conducted flow cytometric and transcriptomic analyses in 23 immune cell subsets deriv...

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Main Authors: Kazuhiko Yamamoto, Mineto Ota, Keishi Fujio, Yasuo Nagafuchi, Tomohisa Okamura, Saeko Yamada, Hirofumi Shoda, Takahiro Itamiya, Toshihiko Komai, Shinji Izuka, Kosuke Matsuki
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:RMD Open
Online Access:https://rmdopen.bmj.com/content/11/2/e005310.full
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