True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors
Abstract Background True umbilical cord knot (TUCK) is frequently missed in prenatal ultrasound (US), hindering standardized management and risk assessment of adverse perinatal outcomes. This study aimed to assess TUCK detection accuracy using active umbilical cord (UC) scanning and identify factors...
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| Format: | Article |
| Language: | English |
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BMC
2025-04-01
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| Series: | BMC Pregnancy and Childbirth |
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| Online Access: | https://doi.org/10.1186/s12884-025-07629-6 |
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| author | Junyan Cao Zhaocong Chen Minhong Zou Miao Zhong Ying Chen Xin Lin Manli Wu Qiaoyuan Wang Xinling Zhang |
| author_facet | Junyan Cao Zhaocong Chen Minhong Zou Miao Zhong Ying Chen Xin Lin Manli Wu Qiaoyuan Wang Xinling Zhang |
| author_sort | Junyan Cao |
| collection | DOAJ |
| description | Abstract Background True umbilical cord knot (TUCK) is frequently missed in prenatal ultrasound (US), hindering standardized management and risk assessment of adverse perinatal outcomes. This study aimed to assess TUCK detection accuracy using active umbilical cord (UC) scanning and identify factors affecting prenatal visualization. Methods A prospective study of 378 pregnant women (11–40 weeks) was conducted. Experienced and novice physicians sequentially scanned the full UC, grading umbilical cord ultrasonic image quality (UCUIQ) as sufficient (scale 1), restricted (scale 2), or poor (scale 3). Factors affecting UCUIQ were analyzed using multiple logistic regression, and diagnostic accuracy was evaluated. Cases for diagnosis were confirmed at delivery. Results Interobserver agreement for UCUIQ grading was excellent (К = 0.979). Gestational week emerged as the primary factor influencing UC visualization (P < 0.05), with ultrasound achieving a diagnostic accuracy of no less than 89.3% for TUCK detection during the 17–26 weeks gestational period. Conclusions Gestational week significantly influenced TUCK detection, with high accuracy at 17–26 weeks. Active UC scanning during this period improved detection accuracy of TUCK. |
| format | Article |
| id | doaj-art-9cfae388f7a6463f9db7bb83b588897d |
| institution | Kabale University |
| issn | 1471-2393 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Pregnancy and Childbirth |
| spelling | doaj-art-9cfae388f7a6463f9db7bb83b588897d2025-08-20T03:52:20ZengBMCBMC Pregnancy and Childbirth1471-23932025-04-012511910.1186/s12884-025-07629-6True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factorsJunyan Cao0Zhaocong Chen1Minhong Zou2Miao Zhong3Ying Chen4Xin Lin5Manli Wu6Qiaoyuan Wang7Xinling Zhang8Department of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Rehabilitation Medicine, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityDepartment of Ultrasound, The Third Affiliated Hospital of Sun Yat-Sen UniversityAbstract Background True umbilical cord knot (TUCK) is frequently missed in prenatal ultrasound (US), hindering standardized management and risk assessment of adverse perinatal outcomes. This study aimed to assess TUCK detection accuracy using active umbilical cord (UC) scanning and identify factors affecting prenatal visualization. Methods A prospective study of 378 pregnant women (11–40 weeks) was conducted. Experienced and novice physicians sequentially scanned the full UC, grading umbilical cord ultrasonic image quality (UCUIQ) as sufficient (scale 1), restricted (scale 2), or poor (scale 3). Factors affecting UCUIQ were analyzed using multiple logistic regression, and diagnostic accuracy was evaluated. Cases for diagnosis were confirmed at delivery. Results Interobserver agreement for UCUIQ grading was excellent (К = 0.979). Gestational week emerged as the primary factor influencing UC visualization (P < 0.05), with ultrasound achieving a diagnostic accuracy of no less than 89.3% for TUCK detection during the 17–26 weeks gestational period. Conclusions Gestational week significantly influenced TUCK detection, with high accuracy at 17–26 weeks. Active UC scanning during this period improved detection accuracy of TUCK.https://doi.org/10.1186/s12884-025-07629-6PregnancyUmbilical cord knotUltrasoundPrenatal diagnosisGestational weeks |
| spellingShingle | Junyan Cao Zhaocong Chen Minhong Zou Miao Zhong Ying Chen Xin Lin Manli Wu Qiaoyuan Wang Xinling Zhang True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors BMC Pregnancy and Childbirth Pregnancy Umbilical cord knot Ultrasound Prenatal diagnosis Gestational weeks |
| title | True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors |
| title_full | True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors |
| title_fullStr | True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors |
| title_full_unstemmed | True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors |
| title_short | True umbilical cord knot detection via active scanning: a prospective study on accuracy and visualization factors |
| title_sort | true umbilical cord knot detection via active scanning a prospective study on accuracy and visualization factors |
| topic | Pregnancy Umbilical cord knot Ultrasound Prenatal diagnosis Gestational weeks |
| url | https://doi.org/10.1186/s12884-025-07629-6 |
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