Caspases: structural and molecular mechanisms and functions in cell death, innate immunity, and disease
Abstract Caspases are critical regulators of cell death, development, innate immunity, host defense, and disease. Upon detection of pathogens, damage-associated molecular patterns, cytokines, or other homeostatic disruptions, innate immune sensors, such as NLRs, activate caspases to initiate distinc...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-05-01
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| Series: | Cell Discovery |
| Online Access: | https://doi.org/10.1038/s41421-025-00791-3 |
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