Photodynamic therapy of basal cell carcinoma of the face H-zone
This article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine...
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| Format: | Article |
| Language: | Russian |
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Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2025-07-01
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| Series: | Biomedical Photonics |
| Subjects: | |
| Online Access: | https://www.pdt-journal.com/jour/article/view/719 |
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| author | E. V. Nadkernichnaya M. V. Ermoschenkova V. E. Semin S. A. Parts V. N. Galkin I. V. Reshetov |
| author_facet | E. V. Nadkernichnaya M. V. Ermoschenkova V. E. Semin S. A. Parts V. N. Galkin I. V. Reshetov |
| author_sort | E. V. Nadkernichnaya |
| collection | DOAJ |
| description | This article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine or photoran at a dose of 0.7 to 2.5 mg per kilogram of patient body weight. The drug was administered intravenously for 30 minutes 2.5-3.0 hours before tumor irradiation. Of 107 observations over a 9-month observation period, one case of marginal tumor recurrence in the treatment area was detected. Thus, the recurrence rate was 0.93%. The results show that three-dimensional tumor visualization for the H-zone with complex noninvasive diagnostics allows achieving high efficiency in photodynamic therapy of non-melanoma tumors of the above anatomical localizations. |
| format | Article |
| id | doaj-art-9cf28a04232644e6818ea0f0f3bf7931 |
| institution | Kabale University |
| issn | 2413-9432 |
| language | Russian |
| publishDate | 2025-07-01 |
| publisher | Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" |
| record_format | Article |
| series | Biomedical Photonics |
| spelling | doaj-art-9cf28a04232644e6818ea0f0f3bf79312025-08-20T03:35:32ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322025-07-0114210.24931/2413-9432-2025-14-2-27-30318Photodynamic therapy of basal cell carcinoma of the face H-zoneE. V. Nadkernichnaya0M. V. Ermoschenkova1V. E. Semin2S. A. Parts3V. N. Galkin4I. V. Reshetov5State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital of the Moscow City Healthcare Department”State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital of the Moscow City Healthcare Department”; First Moscow State Medical University named after I.M. SechenovState Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital of the Moscow City Healthcare Department”State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital of the Moscow City Healthcare Department”State Budgetary Healthcare Institution of the City of Moscow “S.S. Yudin City Clinical Hospital of the Moscow City Healthcare Department”First Moscow State Medical University named after I.M. SechenovThis article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine or photoran at a dose of 0.7 to 2.5 mg per kilogram of patient body weight. The drug was administered intravenously for 30 minutes 2.5-3.0 hours before tumor irradiation. Of 107 observations over a 9-month observation period, one case of marginal tumor recurrence in the treatment area was detected. Thus, the recurrence rate was 0.93%. The results show that three-dimensional tumor visualization for the H-zone with complex noninvasive diagnostics allows achieving high efficiency in photodynamic therapy of non-melanoma tumors of the above anatomical localizations.https://www.pdt-journal.com/jour/article/view/719ultrasound navigationuorescence diagnosticslaser spectroscopynon-melanoma skin tumorslaser spectroscopynon-invasive monitoring |
| spellingShingle | E. V. Nadkernichnaya M. V. Ermoschenkova V. E. Semin S. A. Parts V. N. Galkin I. V. Reshetov Photodynamic therapy of basal cell carcinoma of the face H-zone Biomedical Photonics ultrasound navigation uorescence diagnostics laser spectroscopy non-melanoma skin tumors laser spectroscopy non-invasive monitoring |
| title | Photodynamic therapy of basal cell carcinoma of the face H-zone |
| title_full | Photodynamic therapy of basal cell carcinoma of the face H-zone |
| title_fullStr | Photodynamic therapy of basal cell carcinoma of the face H-zone |
| title_full_unstemmed | Photodynamic therapy of basal cell carcinoma of the face H-zone |
| title_short | Photodynamic therapy of basal cell carcinoma of the face H-zone |
| title_sort | photodynamic therapy of basal cell carcinoma of the face h zone |
| topic | ultrasound navigation uorescence diagnostics laser spectroscopy non-melanoma skin tumors laser spectroscopy non-invasive monitoring |
| url | https://www.pdt-journal.com/jour/article/view/719 |
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