Photodynamic therapy of basal cell carcinoma of the face H-zone
This article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2025-07-01
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| Series: | Biomedical Photonics |
| Subjects: | |
| Online Access: | https://www.pdt-journal.com/jour/article/view/719 |
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| Summary: | This article reviews clinical experience in treating skin neoplasms using photodynamic therapy with combined ultrasound and fluorescence diag- nostics for neoplasms in the nose, lateral face, and adjacent areas. Injectable forms of chlorine-type drugs were used as photosensitizers – photodi- tazine or photoran at a dose of 0.7 to 2.5 mg per kilogram of patient body weight. The drug was administered intravenously for 30 minutes 2.5-3.0 hours before tumor irradiation. Of 107 observations over a 9-month observation period, one case of marginal tumor recurrence in the treatment area was detected. Thus, the recurrence rate was 0.93%. The results show that three-dimensional tumor visualization for the H-zone with complex noninvasive diagnostics allows achieving high efficiency in photodynamic therapy of non-melanoma tumors of the above anatomical localizations. |
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| ISSN: | 2413-9432 |