Nutritional treatment in patients with cardiovascular diseases, hepatic steatosis and metabolic disorders
Background. Cardiovascular diseases remain the leading cause of death in both men and women in industrialized countries. They encompass a variety of conditions, including cerebrovascular disease, peripheral arterial disease, atherosclerosis, and deep vein thrombosis. Non-alcoholic fatty liver disea...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Zaslavsky O.Yu.
2025-06-01
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| Series: | Mìžnarodnij Endokrinologìčnij Žurnal |
| Subjects: | |
| Online Access: | https://iej.zaslavsky.com.ua/index.php/journal/article/view/1561 |
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| Summary: | Background. Cardiovascular diseases remain the leading cause of death in both men and women in industrialized countries. They encompass a variety of conditions, including cerebrovascular disease, peripheral arterial disease, atherosclerosis, and deep vein thrombosis. Non-alcoholic fatty liver disease (NAFLD), also referred to as metabolic dysfunction-associated steatotic liver disease, is characterized by the presence of macro-vesicular steatosis without significant inflammation or alcohol consumption. The purpose of this study was to evaluate the health outcomes associated with the administration of supplements and dietary protocols, developed by the researcher, in patients with various metabolic disorders, including cardiovascular diseases, NAFLD, hypertension, obesity, and type 2 diabetes mellitus. Materials and methods. This study was conducted across the territory of Kosovo, targeting patients who sought treatment for specific health issues. The study period spanned from March 2023 to June 2024, involving participants aged over 18 years, with the main group aged 23–62 years and the control group aged 25–60 years. A total of 73 patients were included, with 33 in the study group and 40 in the control group. The average age of participants was 42.59 ± 12.05 years. Results. Statistically significant differences (p < 0.05) were observed between the study and control groups for several key parameters, including triglycerides (TGL), high-density lipoprotein (HDL), body mass index (BMI), and the homeostasis model assessment of insulin resistance (HOMA-IR). Additionally, significant improvements (p < 0.05) were noted within the study group after 3–6 months of nutritional treatment, particularly in the following diagnostic parameters: TGL, HDL, alanine aminotransferase, BMI, HOMA-IR, and vitamin D. Conclusions. Our study demonstrates that the diet and nutritional supplements recommended by the researchers led to significant improvements in the study group compared to the control one (p < 0.05). |
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| ISSN: | 2224-0721 2307-1427 |