Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour
Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause sh...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Transplantation |
| Online Access: | http://dx.doi.org/10.1155/2016/6801916 |
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| author | Sanjay de Mel Zarni Soe Benjamin Wong Ching Ching Ong Lynette Teo Lip Kun Tan |
| author_facet | Sanjay de Mel Zarni Soe Benjamin Wong Ching Ching Ong Lynette Teo Lip Kun Tan |
| author_sort | Sanjay de Mel |
| collection | DOAJ |
| description | Inflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT. |
| format | Article |
| id | doaj-art-9cec1e65321b45d492da62b5bbacb208 |
| institution | Kabale University |
| issn | 2090-6943 2090-6951 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Transplantation |
| spelling | doaj-art-9cec1e65321b45d492da62b5bbacb2082025-08-20T03:38:15ZengWileyCase Reports in Transplantation2090-69432090-69512016-01-01201610.1155/2016/68019166801916Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory PseudotumourSanjay de Mel0Zarni Soe1Benjamin Wong2Ching Ching Ong3Lynette Teo4Lip Kun Tan5Department of Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeDepartment of Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeDepartment of Pathology, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Diagnostic Imaging, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartment of Diagnostic Imaging, National University Health System, 1E Kent Ridge Road, 119228, SingaporeDepartments of Laboratory Medicine and Haematology-Oncology, National University Cancer Institute, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, 119228, SingaporeInflammatory pseudotumours (IPT) are rare benign neoplasms of unknown aetiology. We present a case of hepatic IPT which was incidentally discovered in a patient with relapsed B-acute lymphoblastic leukaemia (B-ALL) undergoing pretransplant workup. After investigation to exclude an infective cause she underwent a reduced intensity conditioning stem cell transplant (SCT) successfully and currently remains well and in remission. On repeat liver MRI after SCT, the IPT was seen to be resolving. To the best of our knowledge this is the first report of an adult patient with hepatic IPT successfully undergoing SCT. The reduction in size of the IPT after SCT also suggests an inflammatory rather than an infective aetiology for IPT.http://dx.doi.org/10.1155/2016/6801916 |
| spellingShingle | Sanjay de Mel Zarni Soe Benjamin Wong Ching Ching Ong Lynette Teo Lip Kun Tan Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour Case Reports in Transplantation |
| title | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
| title_full | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
| title_fullStr | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
| title_full_unstemmed | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
| title_short | Successful Stem Cell Transplantation in a Patient with Pretransplant Hepatic Inflammatory Pseudotumour |
| title_sort | successful stem cell transplantation in a patient with pretransplant hepatic inflammatory pseudotumour |
| url | http://dx.doi.org/10.1155/2016/6801916 |
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