Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal

The mesoniviruses (MESOVs) belong to the newly described Mesoniviridae family (Order: Nidovirales). They have never been reported in Senegal until recently during a study in arbovirus emergence with the detection of a new species of MESOV named Dianke virus (DKV) from common mosquitoes from eastern...

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Main Authors: Alioune Gaye, Moussa Moïse Diagne, El Hadji Ndiaye, Marie Henriette Dior Ndione, Martin Faye, Cheikh Talla, Gamou Fall, Yamar Ba, Diawo Diallo, Ibrahima Dia, Pascal Handschumacher, Ousmane Faye, Amadou Alpha Sall, Mawlouth Diallo
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Emerging Microbes and Infections
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Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2020.1730710
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author Alioune Gaye
Moussa Moïse Diagne
El Hadji Ndiaye
Marie Henriette Dior Ndione
Martin Faye
Cheikh Talla
Gamou Fall
Yamar Ba
Diawo Diallo
Ibrahima Dia
Pascal Handschumacher
Ousmane Faye
Amadou Alpha Sall
Mawlouth Diallo
author_facet Alioune Gaye
Moussa Moïse Diagne
El Hadji Ndiaye
Marie Henriette Dior Ndione
Martin Faye
Cheikh Talla
Gamou Fall
Yamar Ba
Diawo Diallo
Ibrahima Dia
Pascal Handschumacher
Ousmane Faye
Amadou Alpha Sall
Mawlouth Diallo
author_sort Alioune Gaye
collection DOAJ
description The mesoniviruses (MESOVs) belong to the newly described Mesoniviridae family (Order: Nidovirales). They have never been reported in Senegal until recently during a study in arbovirus emergence with the detection of a new species of MESOV named Dianke virus (DKV) from common mosquitoes from eastern Senegal. Actually, their vector competence for this newly described DKV is unknown. We, therefore, estimated the vector competence of Culex tritaeniorhynchus, Culex quinquefasciatus, Aedes aegypti, and Anopheles gambiae mosquitoes collected in Senegal for DKV using oral infection. Whole bodies, legs/wings, and saliva samples were tested for DKV by RT–PCR to estimate infection, dissemination, and transmission rates. The infectivity of virus particles in the saliva was confirmed by infecting C6/36 cells. Virus transmission rates were up to 95.45% in Culex tritaeniorhynchus, 28% in Cx. quinquefasciatus and 9.09% in Aedes aegypti. Viral particles in the saliva were confirmed infectious by C6/36 cell culture. An. gambiae was able to disseminate DKV only at 20 days post-infection. This study shows that Culex mosquitoes are more competent than Ae. aegypti for DKV, while Anopheles gambiae is not likely a competent vector.
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spelling doaj-art-9cdd3156a04349b390c366cc6258fffd2025-08-20T02:12:20ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512020-01-019149650410.1080/22221751.2020.1730710Vector competence of anthropophilic mosquitoes for a new mesonivirus in SenegalAlioune Gaye0Moussa Moïse Diagne1El Hadji Ndiaye2Marie Henriette Dior Ndione3Martin Faye4Cheikh Talla5Gamou Fall6Yamar Ba7Diawo Diallo8Ibrahima Dia9Pascal Handschumacher10Ousmane Faye11Amadou Alpha Sall12Mawlouth Diallo13Unité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalPole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalUnité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalPole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalPole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalEpidemiology of infectious diseases unit, Institut Pasteur de Dakar, Dakar, SenegalPole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalUnité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalUnité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalUnité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalAix Marseille Univ, INSERM, IRD, UMR SESSTIM, Sciences Economiques & Sociales de la Santé & Traitement de l'Information Médicale, Marseille, FrancePole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalPole de virologie, Unité des Arbovirus et virus de Fièvres Hémorragiques, Institut Pasteur de Dakar, Dakar, SénégalUnité d’Entomologie Médicale, Institut Pasteur de Dakar, Dakar, SénégalThe mesoniviruses (MESOVs) belong to the newly described Mesoniviridae family (Order: Nidovirales). They have never been reported in Senegal until recently during a study in arbovirus emergence with the detection of a new species of MESOV named Dianke virus (DKV) from common mosquitoes from eastern Senegal. Actually, their vector competence for this newly described DKV is unknown. We, therefore, estimated the vector competence of Culex tritaeniorhynchus, Culex quinquefasciatus, Aedes aegypti, and Anopheles gambiae mosquitoes collected in Senegal for DKV using oral infection. Whole bodies, legs/wings, and saliva samples were tested for DKV by RT–PCR to estimate infection, dissemination, and transmission rates. The infectivity of virus particles in the saliva was confirmed by infecting C6/36 cells. Virus transmission rates were up to 95.45% in Culex tritaeniorhynchus, 28% in Cx. quinquefasciatus and 9.09% in Aedes aegypti. Viral particles in the saliva were confirmed infectious by C6/36 cell culture. An. gambiae was able to disseminate DKV only at 20 days post-infection. This study shows that Culex mosquitoes are more competent than Ae. aegypti for DKV, while Anopheles gambiae is not likely a competent vector.https://www.tandfonline.com/doi/10.1080/22221751.2020.1730710Vector competenceDianke virusCulexAedesAnopheles
spellingShingle Alioune Gaye
Moussa Moïse Diagne
El Hadji Ndiaye
Marie Henriette Dior Ndione
Martin Faye
Cheikh Talla
Gamou Fall
Yamar Ba
Diawo Diallo
Ibrahima Dia
Pascal Handschumacher
Ousmane Faye
Amadou Alpha Sall
Mawlouth Diallo
Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
Emerging Microbes and Infections
Vector competence
Dianke virus
Culex
Aedes
Anopheles
title Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
title_full Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
title_fullStr Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
title_full_unstemmed Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
title_short Vector competence of anthropophilic mosquitoes for a new mesonivirus in Senegal
title_sort vector competence of anthropophilic mosquitoes for a new mesonivirus in senegal
topic Vector competence
Dianke virus
Culex
Aedes
Anopheles
url https://www.tandfonline.com/doi/10.1080/22221751.2020.1730710
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