Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema

Lymphedema, characterized by limb swelling, is typically treated with Complex Decongestive Therapy (CDT), which includes physical exercise. This study seeks to design and validate a wearable device aimed at enhancing CDT by monitoring patient adherence to prescribed exercises and tracking changes in...

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Main Authors: Sara Bernasconi, Giovanni Maria Oriolo, Giovanni Farina, Andrea Aliverti, Antonella Lomauro
Format: Article
Language:English
Published: IEEE 2025-01-01
Series:IEEE Journal of Translational Engineering in Health and Medicine
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Online Access:https://ieeexplore.ieee.org/document/10975766/
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author Sara Bernasconi
Giovanni Maria Oriolo
Giovanni Farina
Andrea Aliverti
Antonella Lomauro
author_facet Sara Bernasconi
Giovanni Maria Oriolo
Giovanni Farina
Andrea Aliverti
Antonella Lomauro
author_sort Sara Bernasconi
collection DOAJ
description Lymphedema, characterized by limb swelling, is typically treated with Complex Decongestive Therapy (CDT), which includes physical exercise. This study seeks to design and validate a wearable device aimed at enhancing CDT by monitoring patient adherence to prescribed exercises and tracking changes in the range of motion of the affected limbs. A wearable device, constituted by two boards with 2 IMUs, connected by a flexible flat cable, was designed and developed for placement across targeted joints. It communicates wirelessly with PCs, where raw data from IMUs are collected. Through the application of the Madgwick filter, orientation of the units is obtained and finally joints angles are computed. The device was validated through bench testing using an orthopedic goniometer and field testing with an optoelectronic system. The in vivo validation involved 18 volunteers, including 10 healthy individuals and 8 individuals with lymphedema, who performed flexion-extension movements and walked on a treadmill (at speeds of 3 km/h and 5 km/h). Bench testing demonstrated strong correlation and agreement (r<sup>2</sup>=0.999, mean percentage error = -0.51&#x00B0;, standard deviation = 2.00&#x00B0;). Once worn by the participants, the device enabled the measurement of joint angles during flexion-extension exercises (r<sup>2</sup>=0.852, mean percentage error = 1.44&#x00B0;, standard deviation = 11.7&#x00B0;) and the extraction of step counting, step time and toe off during walk at different speeds. The developed wearable device exhibited robust performance in both bench and field testing. This device, designed specifically for lymphedema patients, offers valuable insights into limb function and exercise adherence, potentially improving personalized treatment strategies.
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spelling doaj-art-9cdc39c607eb4cd9b4c20afc9a5410002025-08-20T02:56:09ZengIEEEIEEE Journal of Translational Engineering in Health and Medicine2168-23722025-01-011319320110.1109/JTEHM.2025.356398510975766Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb LymphedemaSara Bernasconi0https://orcid.org/0000-0002-6641-5001Giovanni Maria Oriolo1https://orcid.org/0009-0005-1441-3345Giovanni Farina2Andrea Aliverti3https://orcid.org/0000-0002-2950-0231Antonella Lomauro4https://orcid.org/0000-0002-1408-6971Dipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, ItalyIstituti Clinici Zucchi di Monza, Monza, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, ItalyDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano, Milan, ItalyLymphedema, characterized by limb swelling, is typically treated with Complex Decongestive Therapy (CDT), which includes physical exercise. This study seeks to design and validate a wearable device aimed at enhancing CDT by monitoring patient adherence to prescribed exercises and tracking changes in the range of motion of the affected limbs. A wearable device, constituted by two boards with 2 IMUs, connected by a flexible flat cable, was designed and developed for placement across targeted joints. It communicates wirelessly with PCs, where raw data from IMUs are collected. Through the application of the Madgwick filter, orientation of the units is obtained and finally joints angles are computed. The device was validated through bench testing using an orthopedic goniometer and field testing with an optoelectronic system. The in vivo validation involved 18 volunteers, including 10 healthy individuals and 8 individuals with lymphedema, who performed flexion-extension movements and walked on a treadmill (at speeds of 3 km/h and 5 km/h). Bench testing demonstrated strong correlation and agreement (r<sup>2</sup>=0.999, mean percentage error = -0.51&#x00B0;, standard deviation = 2.00&#x00B0;). Once worn by the participants, the device enabled the measurement of joint angles during flexion-extension exercises (r<sup>2</sup>=0.852, mean percentage error = 1.44&#x00B0;, standard deviation = 11.7&#x00B0;) and the extraction of step counting, step time and toe off during walk at different speeds. The developed wearable device exhibited robust performance in both bench and field testing. This device, designed specifically for lymphedema patients, offers valuable insights into limb function and exercise adherence, potentially improving personalized treatment strategies.https://ieeexplore.ieee.org/document/10975766/Lymphedemapersonalized treatmentphysical exercise complianceROM detectionwearable device
spellingShingle Sara Bernasconi
Giovanni Maria Oriolo
Giovanni Farina
Andrea Aliverti
Antonella Lomauro
Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
IEEE Journal of Translational Engineering in Health and Medicine
Lymphedema
personalized treatment
physical exercise compliance
ROM detection
wearable device
title Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
title_full Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
title_fullStr Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
title_full_unstemmed Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
title_short Design and Validation of a Wearable System for Enhanced Monitoring of Lower Limb Lymphedema
title_sort design and validation of a wearable system for enhanced monitoring of lower limb lymphedema
topic Lymphedema
personalized treatment
physical exercise compliance
ROM detection
wearable device
url https://ieeexplore.ieee.org/document/10975766/
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