Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release

Background/Aim. The treatment outcome of the median nerve compressive neuropathy in the carpal zone due to carpal tunnel syndrome (CTS) is represented by recovering the nerves sensibility, conductivity, condition and strength. Perineural application of betamethasone during the surgical decompression...

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Main Authors: Stepić Nenad, Novaković Marjan, Martić Vesna, Perić Dušan
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2008-01-01
Series:Vojnosanitetski Pregled
Subjects:
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2008/0042-84500811825S.pdf
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author Stepić Nenad
Novaković Marjan
Martić Vesna
Perić Dušan
author_facet Stepić Nenad
Novaković Marjan
Martić Vesna
Perić Dušan
author_sort Stepić Nenad
collection DOAJ
description Background/Aim. The treatment outcome of the median nerve compressive neuropathy in the carpal zone due to carpal tunnel syndrome (CTS) is represented by recovering the nerves sensibility, conductivity, condition and strength. Perineural application of betamethasone during the surgical decompression might result in faster recovery of compressed median nerve's conduction speed. Methods. In this study 40 patients with CTS were randomly divided in the two groups. In the first group (n = 20) we performed the surgical decompression of the median nerve by the open release of the carpal tunnel, and in the second group (n = 20) we applicated a perineural injection of 1 ml of betamethason immediately after the surgical decompression. We performed the electrodiagnostic (ED) examinations 7, 30 and 90 days after the surgery, and measured the conduction speed of the median nerve in the carpal tunnel zone and the sensitivity conduction speed of the median nerve. Results. Significant differences in examined ED respective variable values in different time intervals were obtained. At the final measurements, 90 days after the surgical procedure, both groups evidenced a full recovery of the conduction speed in the carpal tunnel with statistically significant better results in the second group of the patients (t = -2.116; p = 0.043). Conclusion. Intraoperative application of the corticosteroid injection during the surgical decompression results in faster regaining of conduction speed of the median nerve.
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spelling doaj-art-9cda7d440b1a44ca83c387ded2562a762025-08-20T03:38:15ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502008-01-01651182582910.2298/VSP0811825SEffects of perineural steroid injections on median nerve conduction during the carpal tunnel releaseStepić NenadNovaković MarjanMartić VesnaPerić DušanBackground/Aim. The treatment outcome of the median nerve compressive neuropathy in the carpal zone due to carpal tunnel syndrome (CTS) is represented by recovering the nerves sensibility, conductivity, condition and strength. Perineural application of betamethasone during the surgical decompression might result in faster recovery of compressed median nerve's conduction speed. Methods. In this study 40 patients with CTS were randomly divided in the two groups. In the first group (n = 20) we performed the surgical decompression of the median nerve by the open release of the carpal tunnel, and in the second group (n = 20) we applicated a perineural injection of 1 ml of betamethason immediately after the surgical decompression. We performed the electrodiagnostic (ED) examinations 7, 30 and 90 days after the surgery, and measured the conduction speed of the median nerve in the carpal tunnel zone and the sensitivity conduction speed of the median nerve. Results. Significant differences in examined ED respective variable values in different time intervals were obtained. At the final measurements, 90 days after the surgical procedure, both groups evidenced a full recovery of the conduction speed in the carpal tunnel with statistically significant better results in the second group of the patients (t = -2.116; p = 0.043). Conclusion. Intraoperative application of the corticosteroid injection during the surgical decompression results in faster regaining of conduction speed of the median nerve.http://www.doiserbia.nb.rs/img/doi/0042-8450/2008/0042-84500811825S.pdfcarpal tunnel syndromereconstructive surgical proceduresintraoperative periodbetamethasoneinjectionsmedian nerveelectrodiagnosis
spellingShingle Stepić Nenad
Novaković Marjan
Martić Vesna
Perić Dušan
Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
Vojnosanitetski Pregled
carpal tunnel syndrome
reconstructive surgical procedures
intraoperative period
betamethasone
injections
median nerve
electrodiagnosis
title Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
title_full Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
title_fullStr Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
title_full_unstemmed Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
title_short Effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
title_sort effects of perineural steroid injections on median nerve conduction during the carpal tunnel release
topic carpal tunnel syndrome
reconstructive surgical procedures
intraoperative period
betamethasone
injections
median nerve
electrodiagnosis
url http://www.doiserbia.nb.rs/img/doi/0042-8450/2008/0042-84500811825S.pdf
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AT marticvesna effectsofperineuralsteroidinjectionsonmediannerveconductionduringthecarpaltunnelrelease
AT pericdusan effectsofperineuralsteroidinjectionsonmediannerveconductionduringthecarpaltunnelrelease