Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus

Morvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma d...

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Main Authors: Gabrielle Macaron, Elie El Rassy, Salam Koussa
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2016/9142486
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author Gabrielle Macaron
Elie El Rassy
Salam Koussa
author_facet Gabrielle Macaron
Elie El Rassy
Salam Koussa
author_sort Gabrielle Macaron
collection DOAJ
description Morvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma diagnosis. This paper reports the first case of cooccurrence of SLE, thymic carcinoma, and MoS. The cooccurrence of SLE, thymoma, and MoS delineates the generalized autoimmunity process. Symptoms of both MoS and SLE abated upon tumor resection.
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institution Kabale University
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series Case Reports in Neurological Medicine
spelling doaj-art-9cda22c19a3540e98cf929cc42c64e002025-08-20T03:38:15ZengWileyCase Reports in Neurological Medicine2090-66682090-66762016-01-01201610.1155/2016/91424869142486Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus ErythematosusGabrielle Macaron0Elie El Rassy1Salam Koussa2Department of Neurology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, P.O. Box 166830, Beirut, LebanonDepartment of Neurology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, P.O. Box 166830, Beirut, LebanonDepartment of Neurology, Hotel-Dieu de France University Hospital, Faculty of Medicine, Saint Joseph University, P.O. Box 166830, Beirut, LebanonMorvan syndrome (MoS) is a rare paraneoplastic autoimmune disorder characterized by peripheral nerve hyperexcitability, autonomic dysfunction, and sleep disorders. Systemic lupus erythmatosus (SLE) cooccurs in 6–10% of patients with thymoma. It may occur before, concurrently with, or after thymoma diagnosis. This paper reports the first case of cooccurrence of SLE, thymic carcinoma, and MoS. The cooccurrence of SLE, thymoma, and MoS delineates the generalized autoimmunity process. Symptoms of both MoS and SLE abated upon tumor resection.http://dx.doi.org/10.1155/2016/9142486
spellingShingle Gabrielle Macaron
Elie El Rassy
Salam Koussa
Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
Case Reports in Neurological Medicine
title Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_full Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_fullStr Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_full_unstemmed Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_short Morvan Syndrome Secondary to Thymic Carcinoma in a Patient with Systemic Lupus Erythematosus
title_sort morvan syndrome secondary to thymic carcinoma in a patient with systemic lupus erythematosus
url http://dx.doi.org/10.1155/2016/9142486
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AT elieelrassy morvansyndromesecondarytothymiccarcinomainapatientwithsystemiclupuserythematosus
AT salamkoussa morvansyndromesecondarytothymiccarcinomainapatientwithsystemiclupuserythematosus