Ovarian transcriptome analyses indicate that weak juvenile hormone signaling underlies the molecular basis of oogenesis deficiencies in mosquitoes

Abstract Background Juvenile hormone (JH) is synthesized by the corpora allata (CA) and controls development and reproduction in insects. We recently used CRISPR/Cas9 to establish a line lacking the enzyme that catalyzes the final step of JH biosynthesis in mosquitoes, a P450 epoxidase. The CA of th...

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Bibliographic Details
Main Authors: Monika M. Wiśniewska, Martin Kolísko, Petra Berková, Martin Moos, Houda O. Maaroufi, Fernando G. Noriega, Marcela Nouzova
Format: Article
Language:English
Published: BMC 2025-06-01
Series:BMC Biology
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Online Access:https://doi.org/10.1186/s12915-025-02266-z
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