CD4+RORγt++ and Tregs in a Mouse Model of Diet-Induced Nonalcoholic Steatohepatitis

CD4+RORγt++ and Tregs in a Mouse Model of Diet-Induced Nonalcoholic Steatohepatitis

Background and Aims. Inflammatory mediators that cross-talk in different metabolically active organs are thought to play a crucial role in the pathogenesis of Nonalcoholic Steatohepatitis (NASH). This study was aimed at investigating the CD4+RORγt+ T-helper cells and their counterpart, the CD4+CD25+...

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Main Authors: Luisa Vonghia, Nathalie Ruyssers, Dorien Schrijvers, Paul Pelckmans, Peter Michielsen, Luc De Clerck, Albert Ramon, Emilio Jirillo, Didier Ebo, Benedicte De Winter, Chris Bridts, Sven Francque
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2015/239623
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