Methylated SEPTIN9 plasma test for colorectal cancer detection may be applicable to Lynch syndrome
Objective The plasma-based methylated SEPTIN9 (mSEPT9) is a colorectal cancer (CRC) screening test for adults aged 50–75 years who are at average risk for CRC and have refused colonoscopy or faecal-based screening tests. The applicability of mSEPT9 for high-risk persons with Lynch syndrome (LS), the...
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| Main Authors: | Maria Christensen, Andrew E Hendifar, Rachel Pearlman, Sigurdis Haraldsdottir, Albert de la Chapelle, Heather Hampel, Megan P Hitchins, Ingrid P Vogelaar, Kevin Brennan, Nianmin Zhou, Brock Martin, Rocio Alvarez, Xiaopu Yuan, Sungjin Kim, Maha Guindi, Matthew F Kalady, Jennifer DeVecchio, James M Church, Carrie Snyder, Stephen J Lanspa, Robert W Haile, Henry T Lynch |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2019-08-01
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| Series: | BMJ Open Gastroenterology |
| Online Access: | https://bmjopengastro.bmj.com/content/6/1/e000299.full |
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