Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review

ObjectiveTo present a rare case of mediastinal extraosseous Ewing sarcoma(EES), broadening the body of knowledge already in existence on EES. This paper intends to give doctors more diagnostic and therapeutic understandingMethodsThe patient’s imaging data was analyzed retrospectively. We identified...

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Main Authors: Hong Zhou, Meng Su, Han-Fang Wang, Si-Qi Feng, Wen-Qian Jiang, Xiao-Rong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1578456/full
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author Hong Zhou
Meng Su
Han-Fang Wang
Si-Qi Feng
Wen-Qian Jiang
Xiao-Rong Li
author_facet Hong Zhou
Meng Su
Han-Fang Wang
Si-Qi Feng
Wen-Qian Jiang
Xiao-Rong Li
author_sort Hong Zhou
collection DOAJ
description ObjectiveTo present a rare case of mediastinal extraosseous Ewing sarcoma(EES), broadening the body of knowledge already in existence on EES. This paper intends to give doctors more diagnostic and therapeutic understandingMethodsThe patient’s imaging data was analyzed retrospectively. We identified and compiled the distinctive imaging characteristics of mediastinal EES by combining these results with histopathological evaluation and a review of relevant literature.Key findingsTypical imaging features of mediastinal EES include a large, bulky mass with irregular shape and lobulated, poorly defined margins. On computed tomography (CT), it often shows heterogeneous density along with infiltration of nearby organs and anatomical structures.ConclusionMediastinal EES is a rare and clinically challenging diagnosis. However, recognition of its characteristic imaging features may facilitate radiological diagnosis. Nevertheless, histopathological confirmation remains the gold standard for definitive diagnosis.
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institution DOAJ
issn 2234-943X
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publishDate 2025-06-01
publisher Frontiers Media S.A.
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series Frontiers in Oncology
spelling doaj-art-9cc239006d064cdbb1fbbce0125c6fc92025-08-20T03:22:01ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-06-011510.3389/fonc.2025.15784561578456Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature reviewHong ZhouMeng SuHan-Fang WangSi-Qi FengWen-Qian JiangXiao-Rong LiObjectiveTo present a rare case of mediastinal extraosseous Ewing sarcoma(EES), broadening the body of knowledge already in existence on EES. This paper intends to give doctors more diagnostic and therapeutic understandingMethodsThe patient’s imaging data was analyzed retrospectively. We identified and compiled the distinctive imaging characteristics of mediastinal EES by combining these results with histopathological evaluation and a review of relevant literature.Key findingsTypical imaging features of mediastinal EES include a large, bulky mass with irregular shape and lobulated, poorly defined margins. On computed tomography (CT), it often shows heterogeneous density along with infiltration of nearby organs and anatomical structures.ConclusionMediastinal EES is a rare and clinically challenging diagnosis. However, recognition of its characteristic imaging features may facilitate radiological diagnosis. Nevertheless, histopathological confirmation remains the gold standard for definitive diagnosis.https://www.frontiersin.org/articles/10.3389/fonc.2025.1578456/fullextraskeletal Ewing’s sarcoma(EES)mediastinumcase reportrare sitecomputed tomography
spellingShingle Hong Zhou
Meng Su
Han-Fang Wang
Si-Qi Feng
Wen-Qian Jiang
Xiao-Rong Li
Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
Frontiers in Oncology
extraskeletal Ewing’s sarcoma(EES)
mediastinum
case report
rare site
computed tomography
title Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
title_full Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
title_fullStr Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
title_full_unstemmed Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
title_short Ewing’s sarcoma of the mediastinal extraosseous site: a case report of a rare occurrence with literature review
title_sort ewing s sarcoma of the mediastinal extraosseous site a case report of a rare occurrence with literature review
topic extraskeletal Ewing’s sarcoma(EES)
mediastinum
case report
rare site
computed tomography
url https://www.frontiersin.org/articles/10.3389/fonc.2025.1578456/full
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