Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken
A severe outbreak of Infectious Bursal Disease (IBD) was recorded in 30 chicken flocks in different districts in Sharkia governorate during 2019, with high mortalities (up to 30%) and severe immunosuppression. Attempts to control IBD by an antiviral iron oxide chitosan nanocomposite was conducted. E...
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| Format: | Article |
| Language: | English |
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German Multidisciplinary Publishing Center (GMPC)
2022-01-01
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| Series: | German Journal of Veterinary Research |
| Online Access: | https://doi.org/10.51585/gjvr.2022.3.0041 |
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| author | Soad Nasef Mervat Ayoub Karim Selim Dalia Elmasry |
| author_facet | Soad Nasef Mervat Ayoub Karim Selim Dalia Elmasry |
| author_sort | Soad Nasef |
| collection | DOAJ |
| description | A severe outbreak of Infectious Bursal Disease (IBD) was recorded in 30 chicken flocks in different districts in Sharkia governorate during 2019, with high mortalities (up to 30%) and severe immunosuppression. Attempts to control IBD by an antiviral iron oxide chitosan nanocomposite was conducted. Eighty 21-day-old Baladi broiler chicks were divided into 4 groups. Group A; served as the negative control group, group B; was the challenge control group, group C; was the nanocomposite treatment group, and group D; received nanocomposite. The treatment contained 1 mg/ 100ml IC50 of iron oxide chitosan nanocomposite via the oral route administered for 3 days post-infection (PI). Results revealed that the iron oxide chitosan nanocomposite nano-size was 35.1±5nm with a stable state, zeta potentials16.8 ± 10.9, the PDI 0.91 and iron concentration in nanocomposite was 2625 mg/L. The virus shedding showed a significant decrease (P |
| format | Article |
| id | doaj-art-9cc1264ed5cf4a73b7ab9d0720aca3c8 |
| institution | OA Journals |
| issn | 2703-1322 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | German Multidisciplinary Publishing Center (GMPC) |
| record_format | Article |
| series | German Journal of Veterinary Research |
| spelling | doaj-art-9cc1264ed5cf4a73b7ab9d0720aca3c82025-08-20T01:59:48ZengGerman Multidisciplinary Publishing Center (GMPC)German Journal of Veterinary Research2703-13222022-01-01172710.51585/gjvr.2022.3.0041Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chickenSoad NasefMervat AyoubKarim SelimDalia ElmasryA severe outbreak of Infectious Bursal Disease (IBD) was recorded in 30 chicken flocks in different districts in Sharkia governorate during 2019, with high mortalities (up to 30%) and severe immunosuppression. Attempts to control IBD by an antiviral iron oxide chitosan nanocomposite was conducted. Eighty 21-day-old Baladi broiler chicks were divided into 4 groups. Group A; served as the negative control group, group B; was the challenge control group, group C; was the nanocomposite treatment group, and group D; received nanocomposite. The treatment contained 1 mg/ 100ml IC50 of iron oxide chitosan nanocomposite via the oral route administered for 3 days post-infection (PI). Results revealed that the iron oxide chitosan nanocomposite nano-size was 35.1±5nm with a stable state, zeta potentials16.8 ± 10.9, the PDI 0.91 and iron concentration in nanocomposite was 2625 mg/L. The virus shedding showed a significant decrease (Phttps://doi.org/10.51585/gjvr.2022.3.0041 |
| spellingShingle | Soad Nasef Mervat Ayoub Karim Selim Dalia Elmasry Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken German Journal of Veterinary Research |
| title | Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| title_full | Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| title_fullStr | Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| title_full_unstemmed | Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| title_short | Trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| title_sort | trial to control infectious bursal disease virus using iron oxide chitosan nanocomposite in broiler chicken |
| url | https://doi.org/10.51585/gjvr.2022.3.0041 |
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