Rare cases of primarily infected kidney graft transplantation with the development of purulent complications
Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxi...
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| Format: | Article |
| Language: | English |
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N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department
2024-09-01
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| Series: | Трансплантология (Москва) |
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| Online Access: | https://www.jtransplantologiya.ru/jour/article/view/918 |
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| author | N. V. Shmarina K. E. Lazareva I. V. Dmitriev A. G. Balkarov D. V. Lonshakov N. S. Zhuravel V. V. Smirnova |
| author_facet | N. V. Shmarina K. E. Lazareva I. V. Dmitriev A. G. Balkarov D. V. Lonshakov N. S. Zhuravel V. V. Smirnova |
| author_sort | N. V. Shmarina |
| collection | DOAJ |
| description | Background. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis.Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients.Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes.Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life. |
| format | Article |
| id | doaj-art-9cbff11a94524335bcdb63da91464a1b |
| institution | Kabale University |
| issn | 2074-0506 2542-0909 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | N.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare Department |
| record_format | Article |
| series | Трансплантология (Москва) |
| spelling | doaj-art-9cbff11a94524335bcdb63da91464a1b2025-08-20T03:56:36ZengN.V. Sklifosovsky Research Institute for Emergency Medicine of Moscow Healthcare DepartmentТрансплантология (Москва)2074-05062542-09092024-09-0116335336310.23873/2074-0506-2024-16-3-353-363626Rare cases of primarily infected kidney graft transplantation with the development of purulent complicationsN. V. Shmarina0K. E. Lazareva1I. V. Dmitriev2A. G. Balkarov3D. V. Lonshakov4N. S. Zhuravel5V. V. Smirnova6N.V. Sklifosovsky Research Institute for Emergency Medicine ; Department of Transplantology and Artificial Organs, N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine ; Department of Transplantology and Artificial Organs of the Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine ; Department of Transplantology and Artificial Organs, N.I. Pirogov Russian National Research Medical UniversityN.V. Sklifosovsky Research Institute for Emergency Medicine ; Department of Transplantology and Artificial Organs, N.I. Pirogov Russian National Research Medical University ; Research Institute for Healthcare Organization and Medical ManagementN.V. Sklifosovsky Research Institute for Emergency MedicineN.V. Sklifosovsky Research Institute for Emergency Medicine ; Department of Transplantology and Artificial Organs of the Scientific and Educational Institute "N.A. Semashko Higher School of Clinical Medicine", Russian University of MedicineN.V. Sklifosovsky Research Institute for Emergency MedicineBackground. Unexpected transmission of an infectious disease agent with a kidney graft to a recipient is a rare event but it is associated with significant morbidity and mortality, especially when exposed to multidrug-resistant bacteria that have not been eliminated by standard antibiotic prophylaxis.Objective. To demonstrate the need for immediate removal of a primary infected kidney graft in the event of local purulent complications due to the rapid development of sepsis in immunocompromised patients.Results. The paper describes a clinical course of the infectious process in two kidney recipients each of whom underwent transplantation of a primary infected graft from a single donor, taking into consideration the transplantectomy timing and the treatment outcomes.Conclusion. The Case Report shows the need for immediate transplantectomy in a kidney graft recipient when local purulent complications are detected with confirmed primary infection of the graft due to a high risk of the rapid development of sepsis and threat to life.https://www.jtransplantologiya.ru/jour/article/view/918kidney transplantationprimary graft infectioninfectious complicationspurulent complications after kidney transplantationseptic complications after kidney transplantation |
| spellingShingle | N. V. Shmarina K. E. Lazareva I. V. Dmitriev A. G. Balkarov D. V. Lonshakov N. S. Zhuravel V. V. Smirnova Rare cases of primarily infected kidney graft transplantation with the development of purulent complications Трансплантология (Москва) kidney transplantation primary graft infection infectious complications purulent complications after kidney transplantation septic complications after kidney transplantation |
| title | Rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| title_full | Rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| title_fullStr | Rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| title_full_unstemmed | Rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| title_short | Rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| title_sort | rare cases of primarily infected kidney graft transplantation with the development of purulent complications |
| topic | kidney transplantation primary graft infection infectious complications purulent complications after kidney transplantation septic complications after kidney transplantation |
| url | https://www.jtransplantologiya.ru/jour/article/view/918 |
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