Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer

Tumor cell-derived EMP1 is essential for cancer-associated fibroblast infiltration in tumor microenvironment of triple-negative breast cancer

Abstract The role of epithelial membrane protein 1 (EMP1) in tumor microenvironment (TME) remodeling has not yet been elucidated. In addition, the biological function of EMP1 in triple-negative breast cancer (TNBC) is largely unclear. In this study, we examined the infiltration landscape of cell typ...

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Main Authors: Qi Wang, Dandan Li, Haixiu Ma, Zengyan Li, Juan Wu, Jinwan Qiao, Jun Liu, Jing Zhao, Ronghua Ma, Lin Tian, Lei Zhang, Jianye Yang, Jianing Wang, Shanshan Qin, Zhanhai Su
Format: Article
Language:English
Published: Nature Publishing Group 2025-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07464-9
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