TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size.

Pathological cardiac hypertrophy is associated with an increased risk of heart failure and cardiovascular mortality. Calcium (Ca(2+)) -regulated gene expression is essential for the induction of hypertrophy, but it is not known how myocytes distinguish between the Ca(2+) signals that regulate contra...

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Bibliographic Details
Main Authors: Jacob S Brenner, Ricardo E Dolmetsch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-08-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0000802&type=printable
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