Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease
Introduction: Triatomines are vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Currently, there is no vaccine against this disease. Thus, control of the insect vector population is the main strategy available to reduce the number of cases. Triatomines are considered obligate he...
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Frontiers Media S.A.
2024-10-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2024.1360255/full |
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| author | Mariana C. Costa Carlos J. C. Moreira Pedro Lagerblad de Oliveira Pedro Lagerblad de Oliveira José Juberg Daniele Pereira de Castro Daniele Pereira de Castro Fernando Ariel Genta Fernando Ariel Genta |
| author_facet | Mariana C. Costa Carlos J. C. Moreira Pedro Lagerblad de Oliveira Pedro Lagerblad de Oliveira José Juberg Daniele Pereira de Castro Daniele Pereira de Castro Fernando Ariel Genta Fernando Ariel Genta |
| author_sort | Mariana C. Costa |
| collection | DOAJ |
| description | Introduction: Triatomines are vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Currently, there is no vaccine against this disease. Thus, control of the insect vector population is the main strategy available to reduce the number of cases. Triatomines are considered obligate hematophagous, but different alternative feeding behaviors were described, such as haemolymphagy or plant feeding.Methods: To determine the preference for sugar feeding in nymphs and adults of Rhodnius prolixus, the insects were exposed a piece of cotton containing bromophenol blue plus sucrose. In addition, we offered several sugars for different species of triatomines, and tested sugar meals as a route of delivery of insecticides in first-instar nymphs of R. prolixus. The effect of sugar feeding on the physiology of these different species of triatomines was recorded.Results: First instar nymphs ingested sucrose more strongly than other stages, and showed high mortality rates. In different species of triatomines, sucrose induced an ingestion, but engorgement varied according to the species. R. prolixus nymphs showed an indiscriminate intake of various sugars, with very different physiological effects. Furthermore, ingesting different combinations of insecticides + sugar significantly reduced insect survival.Discussion: In summary, we described for the first-time sugar feeding as a widespread behavior in several species of triatomines, and the possibility of the use of toxic sugar baits for the control of these vectors. The knowledge of feeding behavior in these insects can be fundamental for the development of new strategies to control Chagas disease. |
| format | Article |
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| institution | OA Journals |
| issn | 1664-042X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj-art-9cb3ae546eb842bcbc395a4e19a2d2e52025-08-20T02:17:06ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2024-10-011510.3389/fphys.2024.13602551360255Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas diseaseMariana C. Costa0Carlos J. C. Moreira1Pedro Lagerblad de Oliveira2Pedro Lagerblad de Oliveira3José Juberg4Daniele Pereira de Castro5Daniele Pereira de Castro6Fernando Ariel Genta7Fernando Ariel Genta8Laboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilLaboratório de Doenças Parasitárias, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilLaboratório de Bioquímica de Artrópodes Hematófagos, Centro de Ciências da Saúde, Universidade Federal do Rio de Janeiro, Rio de Janeiro, BrazilInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, BrazilLaboratório Nacional e Internacional de Referência em Taxonomia de Triatomíneos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilLaboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, BrazilLaboratório de Bioquímica e Fisiologia de Insetos, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, BrazilInstituto Nacional de Ciência e Tecnologia em Entomologia Molecular, Rio de Janeiro, BrazilIntroduction: Triatomines are vectors of Trypanosoma cruzi, the etiological agent of Chagas disease. Currently, there is no vaccine against this disease. Thus, control of the insect vector population is the main strategy available to reduce the number of cases. Triatomines are considered obligate hematophagous, but different alternative feeding behaviors were described, such as haemolymphagy or plant feeding.Methods: To determine the preference for sugar feeding in nymphs and adults of Rhodnius prolixus, the insects were exposed a piece of cotton containing bromophenol blue plus sucrose. In addition, we offered several sugars for different species of triatomines, and tested sugar meals as a route of delivery of insecticides in first-instar nymphs of R. prolixus. The effect of sugar feeding on the physiology of these different species of triatomines was recorded.Results: First instar nymphs ingested sucrose more strongly than other stages, and showed high mortality rates. In different species of triatomines, sucrose induced an ingestion, but engorgement varied according to the species. R. prolixus nymphs showed an indiscriminate intake of various sugars, with very different physiological effects. Furthermore, ingesting different combinations of insecticides + sugar significantly reduced insect survival.Discussion: In summary, we described for the first-time sugar feeding as a widespread behavior in several species of triatomines, and the possibility of the use of toxic sugar baits for the control of these vectors. The knowledge of feeding behavior in these insects can be fundamental for the development of new strategies to control Chagas disease.https://www.frontiersin.org/articles/10.3389/fphys.2024.1360255/fulltriatominesugar feedingChagas diseaseattractive toxic sugar bait (ATSB)Rhodnius prolixus |
| spellingShingle | Mariana C. Costa Carlos J. C. Moreira Pedro Lagerblad de Oliveira Pedro Lagerblad de Oliveira José Juberg Daniele Pereira de Castro Daniele Pereira de Castro Fernando Ariel Genta Fernando Ariel Genta Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease Frontiers in Physiology triatomine sugar feeding Chagas disease attractive toxic sugar bait (ATSB) Rhodnius prolixus |
| title | Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease |
| title_full | Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease |
| title_fullStr | Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease |
| title_full_unstemmed | Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease |
| title_short | Sugar feeding in triatomines: a new perspective for controlling the transmission of Chagas disease |
| title_sort | sugar feeding in triatomines a new perspective for controlling the transmission of chagas disease |
| topic | triatomine sugar feeding Chagas disease attractive toxic sugar bait (ATSB) Rhodnius prolixus |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2024.1360255/full |
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