Expression Pattern and Prognostic Significance of Aldehyde Dehydrogenase 2 in Lung Adenocarcinoma as a Potential Predictor of Immunotherapy Efficacy

Abstract Background The incidence of alcohol‐associated cancers is higher within Asian populations having an increased prevalence of an inactivating mutation in aldehyde dehydrogenase 2 (ALDH2), a mitochondrial enzyme required for the clearance of acetaldehyde, a cytotoxic metabolite of ethanol. The...

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Bibliographic Details
Main Authors: Silvia Baldari, Annalisa Antonini, Giuliana Di Rocco, Gabriele Toietta
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Cancer Innovation
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Online Access:https://doi.org/10.1002/cai2.149
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