Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya

Bacterial antimicrobial resistance (AMR) is a global threat to both human and animal health. This is mainly because the same antimicrobial molecules are used for the treatment and prophylaxis of bacterial diseases in both cases, and about 60% of human pathogens are shared with animals. For effective...

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Main Authors: Tino A. Deng, Lilly C. Bebora, Mahacla O. Odongo, Gerald M. Muchemi, Samuel Karuki, Peter K. Gathumi
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Veterinary Medicine International
Online Access:http://dx.doi.org/10.1155/2024/9921963
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author Tino A. Deng
Lilly C. Bebora
Mahacla O. Odongo
Gerald M. Muchemi
Samuel Karuki
Peter K. Gathumi
author_facet Tino A. Deng
Lilly C. Bebora
Mahacla O. Odongo
Gerald M. Muchemi
Samuel Karuki
Peter K. Gathumi
author_sort Tino A. Deng
collection DOAJ
description Bacterial antimicrobial resistance (AMR) is a global threat to both human and animal health. This is mainly because the same antimicrobial molecules are used for the treatment and prophylaxis of bacterial diseases in both cases, and about 60% of human pathogens are shared with animals. For effective control of AMR in any country, the current situation has to be established; this is done through surveillance exercises. In Kenya, there is scanty data on the prevailing AMR situation, especially in animals. This paper reports on AMR profiles of 54 E. coli strains isolated from chickens in a cross-sectional study, out of which 36/54 (72%) were from clinically ill chickens, 11/54 (22%) were from farm chickens, and 7/54 (9.7%) were from slaughtered chicken, respectively. All 54 isolates exhibited varying antimicrobial resistance profiles with the majority showing resistance to Ampicillin (85.22%), Tetracycline (66.7%), Co-trimoxazole (57.4%), and Streptomycin (40.7%). Very few isolates were resistant to Amoxicillin and Gentamicin (each at 3.7%), Ampicillin (11.1%), and Nalidixic acid (24.1%). A total of 44/54 (81.5%) showed multiple resistance to up to 6 antimicrobial agents. This information will augment current data on the AMR status of bacteria harbored by chickens in Kenya. It will also inform policymakers in their fight against AMR.
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spelling doaj-art-9ca77401903741b58396720f3db3eb082025-08-20T03:38:16ZengWileyVeterinary Medicine International2042-00482024-01-01202410.1155/2024/9921963Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, KenyaTino A. Deng0Lilly C. Bebora1Mahacla O. Odongo2Gerald M. Muchemi3Samuel Karuki4Peter K. Gathumi5Department of Veterinary Pathology, Microbiology and ParasitologyDepartment of Veterinary Pathology, Microbiology and ParasitologyDepartment of Veterinary Pathology, Microbiology and ParasitologyDepartment of Public Health, Pharmacology and ToxicologyCenter for Microbiology ResearchDepartment of Veterinary Pathology, Microbiology and ParasitologyBacterial antimicrobial resistance (AMR) is a global threat to both human and animal health. This is mainly because the same antimicrobial molecules are used for the treatment and prophylaxis of bacterial diseases in both cases, and about 60% of human pathogens are shared with animals. For effective control of AMR in any country, the current situation has to be established; this is done through surveillance exercises. In Kenya, there is scanty data on the prevailing AMR situation, especially in animals. This paper reports on AMR profiles of 54 E. coli strains isolated from chickens in a cross-sectional study, out of which 36/54 (72%) were from clinically ill chickens, 11/54 (22%) were from farm chickens, and 7/54 (9.7%) were from slaughtered chicken, respectively. All 54 isolates exhibited varying antimicrobial resistance profiles with the majority showing resistance to Ampicillin (85.22%), Tetracycline (66.7%), Co-trimoxazole (57.4%), and Streptomycin (40.7%). Very few isolates were resistant to Amoxicillin and Gentamicin (each at 3.7%), Ampicillin (11.1%), and Nalidixic acid (24.1%). A total of 44/54 (81.5%) showed multiple resistance to up to 6 antimicrobial agents. This information will augment current data on the AMR status of bacteria harbored by chickens in Kenya. It will also inform policymakers in their fight against AMR.http://dx.doi.org/10.1155/2024/9921963
spellingShingle Tino A. Deng
Lilly C. Bebora
Mahacla O. Odongo
Gerald M. Muchemi
Samuel Karuki
Peter K. Gathumi
Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
Veterinary Medicine International
title Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
title_full Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
title_fullStr Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
title_full_unstemmed Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
title_short Antimicrobial Resistance Profiles of E. coli Isolated From Pooled Samples of Sick, Farm, and Market Chickens in Nairobi County, Kenya
title_sort antimicrobial resistance profiles of e coli isolated from pooled samples of sick farm and market chickens in nairobi county kenya
url http://dx.doi.org/10.1155/2024/9921963
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