MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations

Objective: This parallel cohort-implementation study, termed MonitOring the health Trajectory of patients with kNee osteoarthritis (MOTION), aims to understand treatment pathways and outcomes for people with knee osteoarthritis referred to Australian public hospitals for orthopaedic assessment (Part...

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Main Authors: Christian J. Barton, Michelle Dowsey, Anne Smith, Ilana N. Ackerman, Zanfina Ademi, Samantha Bunzli, Peter Choong, Kay M. Crossley, Joanne Kemp, Jason A. Wallis, Alison Gibbs, Vincent Lengkong, Allison M. Ezzat, Juanita Low, Zhomart Orman, Nicholas F. Taylor, Anna Wong Shee, Natasha A. Lannin, Ewa M. Roos, Raph Hau, Angela Cochrane, Mia Pithie, Emma Draffin, David Mitchell, Trevor Russell, Danilo De Oliveira Silva
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Osteoarthritis and Cartilage Open
Online Access:http://www.sciencedirect.com/science/article/pii/S2665913125000585
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author Christian J. Barton
Michelle Dowsey
Anne Smith
Ilana N. Ackerman
Zanfina Ademi
Samantha Bunzli
Peter Choong
Kay M. Crossley
Joanne Kemp
Jason A. Wallis
Alison Gibbs
Vincent Lengkong
Allison M. Ezzat
Juanita Low
Zhomart Orman
Nicholas F. Taylor
Anna Wong Shee
Natasha A. Lannin
Ewa M. Roos
Raph Hau
Angela Cochrane
Mia Pithie
Emma Draffin
David Mitchell
Trevor Russell
Danilo De Oliveira Silva
author_facet Christian J. Barton
Michelle Dowsey
Anne Smith
Ilana N. Ackerman
Zanfina Ademi
Samantha Bunzli
Peter Choong
Kay M. Crossley
Joanne Kemp
Jason A. Wallis
Alison Gibbs
Vincent Lengkong
Allison M. Ezzat
Juanita Low
Zhomart Orman
Nicholas F. Taylor
Anna Wong Shee
Natasha A. Lannin
Ewa M. Roos
Raph Hau
Angela Cochrane
Mia Pithie
Emma Draffin
David Mitchell
Trevor Russell
Danilo De Oliveira Silva
author_sort Christian J. Barton
collection DOAJ
description Objective: This parallel cohort-implementation study, termed MonitOring the health Trajectory of patients with kNee osteoarthritis (MOTION), aims to understand treatment pathways and outcomes for people with knee osteoarthritis referred to Australian public hospitals for orthopaedic assessment (Part A cohort study), and how improving access to first-line care might improve outcomes (Part B implementation study). Methods and analysis: We will recruit approximately 400 adults with knee osteoarthritis referred for orthopaedic opinion to one of four public hospitals in Victoria, Australia. A subgroup enrolled in the study (n ​= ​109) will receive improved access to community-based first-line care. Outcomes will be evaluated at baseline, 4-, 8-, 12- (primary end point), 24- and 60-months. The primary outcome will divide the cohort into 1's (willing to undergo, waitlisting for, or undergone, TKR surgery) or 0's (not willing to undergo, not undergone, and not waitlisted for, TKR surgery). Secondary outcomes include pain, knee- and health-related quality of life, physical activity participation and health care utilisation. Surgical and health trajectories will be reported descriptively, with factors associated with outcomes explored. The effectiveness of improving access to first-line care will be determined through propensity score methods. The cost-effectiveness of improving access to first-line care will be also be determined, and semi-structured interviews (1:1 and focus groups) involving participants, health professionals, administrators, and research team will inform a comprehensive process evaluation. Ethics and dissemination: Approved by St Vincent's Hospital Melbourne Human Research Ethics Committee (HREC 251/21). Findings will be disseminated to stakeholders including via conferences, peer-reviewed journals, and social and mainstream media.
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spelling doaj-art-9ca0de083f274009aa392a1afde0b7aa2025-08-20T03:05:52ZengElsevierOsteoarthritis and Cartilage Open2665-91312025-09-017310062210.1016/j.ocarto.2025.100622MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and LimitationsChristian J. Barton0Michelle Dowsey1Anne Smith2Ilana N. Ackerman3Zanfina Ademi4Samantha Bunzli5Peter Choong6Kay M. Crossley7Joanne Kemp8Jason A. Wallis9Alison Gibbs10Vincent Lengkong11Allison M. Ezzat12Juanita Low13Zhomart Orman14Nicholas F. Taylor15Anna Wong Shee16Natasha A. Lannin17Ewa M. Roos18Raph Hau19Angela Cochrane20Mia Pithie21Emma Draffin22David Mitchell23Trevor Russell24Danilo De Oliveira Silva25Department of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; Corresponding author. Department of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia.Department of Orthopaedics, St Vincent's Hospital, Victoria, Australia; University of Melbourne Department of Surgery, St. Vincent's Hospital, Melbourne, Victoria, AustraliaSchool of Allied Health, Curtin University, Perth, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, AustraliaCentre for Medicine Use and Safety, Monash University, Melbourne, AustraliaSchool of Health Sciences and Social Work, Griffith University, Queensland, Australia; Physiotherapy Department, Royal Brisbane and Women's Hospital, Queensland, AustraliaDepartment of Orthopaedics, St Vincent's Hospital, Victoria, Australia; University of Melbourne Department of Surgery, St. Vincent's Hospital, Melbourne, Victoria, AustraliaLa Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, AustraliaLa Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, AustraliaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; Physiotherapy Department, Eastern Health, Box Hill Hospital, Victoria, AustraliaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; Physiotherapy Department, Eastern Health, Box Hill Hospital, Victoria, AustraliaLa Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; Department of Physical Therapy, University of British Columbia, Vancouver, CanadaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, AustraliaSchool of Public Health and Preventive Medicine, Monash University, Melbourne, AustraliaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; Allied Health Clinical Research Office, Eastern Health, Box Hill, AustraliaGrampians Health, Ballarat, Australia; Deakin Rural Health, Deakin University, Warrnambool, AustraliaBrain Recovery and Rehabilitation Group, Department of Neuroscience, School of Translational Medicine, Monash University, Melbourne, VIC, AustraliaDepartment of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, DenmarkDepartment of Surgery, Eastern Health, Box Hill Hospital, Victoria, AustraliaDepartment of Orthopaedics, St Vincent's Hospital, Victoria, Australia; University of Melbourne Department of Surgery, St. Vincent's Hospital, Melbourne, Victoria, AustraliaGrampians Health, Ballarat, AustraliaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, AustraliaGrampians Health, Ballarat, AustraliaRECOVER Injury Research Centre, The University of Queensland, Herston, Queensland, AustraliaDepartment of Physiotherapy, Podiatry and Prosthetics and Orthotics, La Trobe University, School of Allied Health Human Services and Sport, Melbourne, Victoria, Australia; La Trobe Sport and Exercise Medicine Research Centre, La Trobe University School of Allied Health Human Services and Sport, Melbourne, Victoria, AustraliaObjective: This parallel cohort-implementation study, termed MonitOring the health Trajectory of patients with kNee osteoarthritis (MOTION), aims to understand treatment pathways and outcomes for people with knee osteoarthritis referred to Australian public hospitals for orthopaedic assessment (Part A cohort study), and how improving access to first-line care might improve outcomes (Part B implementation study). Methods and analysis: We will recruit approximately 400 adults with knee osteoarthritis referred for orthopaedic opinion to one of four public hospitals in Victoria, Australia. A subgroup enrolled in the study (n ​= ​109) will receive improved access to community-based first-line care. Outcomes will be evaluated at baseline, 4-, 8-, 12- (primary end point), 24- and 60-months. The primary outcome will divide the cohort into 1's (willing to undergo, waitlisting for, or undergone, TKR surgery) or 0's (not willing to undergo, not undergone, and not waitlisted for, TKR surgery). Secondary outcomes include pain, knee- and health-related quality of life, physical activity participation and health care utilisation. Surgical and health trajectories will be reported descriptively, with factors associated with outcomes explored. The effectiveness of improving access to first-line care will be determined through propensity score methods. The cost-effectiveness of improving access to first-line care will be also be determined, and semi-structured interviews (1:1 and focus groups) involving participants, health professionals, administrators, and research team will inform a comprehensive process evaluation. Ethics and dissemination: Approved by St Vincent's Hospital Melbourne Human Research Ethics Committee (HREC 251/21). Findings will be disseminated to stakeholders including via conferences, peer-reviewed journals, and social and mainstream media.http://www.sciencedirect.com/science/article/pii/S2665913125000585
spellingShingle Christian J. Barton
Michelle Dowsey
Anne Smith
Ilana N. Ackerman
Zanfina Ademi
Samantha Bunzli
Peter Choong
Kay M. Crossley
Joanne Kemp
Jason A. Wallis
Alison Gibbs
Vincent Lengkong
Allison M. Ezzat
Juanita Low
Zhomart Orman
Nicholas F. Taylor
Anna Wong Shee
Natasha A. Lannin
Ewa M. Roos
Raph Hau
Angela Cochrane
Mia Pithie
Emma Draffin
David Mitchell
Trevor Russell
Danilo De Oliveira Silva
MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
Osteoarthritis and Cartilage Open
title MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
title_full MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
title_fullStr MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
title_full_unstemmed MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
title_short MonitOring the health trajectory of patients with kNee osteoarthritis referred for orthopaedic opinion: Protocol for the MOTION parallel cohort-implementation studyStrengths and Limitations
title_sort monitoring the health trajectory of patients with knee osteoarthritis referred for orthopaedic opinion protocol for the motion parallel cohort implementation studystrengths and limitations
url http://www.sciencedirect.com/science/article/pii/S2665913125000585
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