Cholinergic modulation of neural networks supports sequential and complementary roles for NREM and REM states in memory consolidation.

Across vertebrate species, sleep consists of repeating cycles of NREM followed by REM. However, their respective functions, and their stereotypic cycling pattern are not well understood. Using a simplified biophysical network model, we investigate the potential role of cholinergic modulation, acting...

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Bibliographic Details
Main Authors: Michael Satchell, Edith Butel-Fry, Zahraa Noureddine, Alexis Simmons, Nicolette Ognjanovski, Sara J Aton, Michal R Zochowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1013097
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