The influence of different food types on the morphological characteristics of rat small intestines
Multiple studies have shown the importance of adequate nutrition for animals and humans and its effect on overall health. Therefore, the aim of this study was to investigate the effects of different nutritional regimes on the intestinal health of rats by evaluating different morphological and morpho...
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Ss.Cyril and Methodius University, Skopje
2025-03-01
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| Series: | Macedonian Veterinary Review |
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| Online Access: | https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2025_0010 |
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| author | Nedžad Hadžiomerović Fuad Babović Anel Vejzović Aida Bešić Elvir Čičkušić Nejra Dučić Muhamed Katica |
| author_facet | Nedžad Hadžiomerović Fuad Babović Anel Vejzović Aida Bešić Elvir Čičkušić Nejra Dučić Muhamed Katica |
| author_sort | Nedžad Hadžiomerović |
| collection | DOAJ |
| description | Multiple studies have shown the importance of adequate nutrition for animals and humans and its effect on overall health. Therefore, the aim of this study was to investigate the effects of different nutritional regimes on the intestinal health of rats by evaluating different morphological and morphometric characteristics of small intestines, with the emphasis on the villus height:crypt depth ratio (V:C). For the experimental study, 24 clinically healthy adult Wistar rats were used. The rats were randomly divided into 3 groups: the control group (group A) was fed with conventional food, the second group (group B) with bakery products, and the third group (group C) with meat products. Samples of the duodenum and jejunum were collected for detailed morphological and morphometric analysis. A significant increase in the duodenal villi height was reported in group B (661.59 μm) and C (602.83 μm) compared to the control group (475.34 μm). The crypt depth values in the jejunum were significantly higher in group B (191.41μm) and C (246.23 μm) compared with the control (145.14 μm). The jejunal V:C ratio was significantly lower in groups B and C. The study showed significant morphological changes in the intestinal parameters in rats fed predominantly with meat and bakery products. These findings could be applicable in both veterinary and human medicine, underlining the significance of consumed food on gut health. |
| format | Article |
| id | doaj-art-9c903f58e2584dcd86042595e71a643d |
| institution | DOAJ |
| issn | 1409-7621 1857-7415 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Ss.Cyril and Methodius University, Skopje |
| record_format | Article |
| series | Macedonian Veterinary Review |
| spelling | doaj-art-9c903f58e2584dcd86042595e71a643d2025-08-20T03:01:57ZengSs.Cyril and Methodius University, SkopjeMacedonian Veterinary Review1409-76211857-74152025-03-0148151310.2478/macvetrev-2025-0010The influence of different food types on the morphological characteristics of rat small intestinesNedžad Hadžiomerović0https://orcid.org/0000-0002-3155-1011Fuad Babović1https://orcid.org/0009-0006-3704-4009Anel Vejzović2https://orcid.org/0009-0005-7174-0369Aida Bešić3https://orcid.org/0000-0001-9157-6942Elvir Čičkušić4https://orcid.org/0000-0002-1053-7499Nejra Dučić5https://orcid.org/0000-0002-1373-8640Muhamed Katica6https://orcid.org/0000-0002-8184-0065Department of Basic Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaDepartment of Basic Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaDepartment of Basic Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaDepartment of Clinical Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaPathology Clinic, University Clinical Center Tuzla, University of Tuzla, Tuzla, Bosnia and HerzegovinaDepartment of Basic Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaDepartment of Clinical Sciences of Veterinary Medicine, Veterinary Faculty, University of Sarajevo, Sarajevo, Bosnia and HerzegovinaMultiple studies have shown the importance of adequate nutrition for animals and humans and its effect on overall health. Therefore, the aim of this study was to investigate the effects of different nutritional regimes on the intestinal health of rats by evaluating different morphological and morphometric characteristics of small intestines, with the emphasis on the villus height:crypt depth ratio (V:C). For the experimental study, 24 clinically healthy adult Wistar rats were used. The rats were randomly divided into 3 groups: the control group (group A) was fed with conventional food, the second group (group B) with bakery products, and the third group (group C) with meat products. Samples of the duodenum and jejunum were collected for detailed morphological and morphometric analysis. A significant increase in the duodenal villi height was reported in group B (661.59 μm) and C (602.83 μm) compared to the control group (475.34 μm). The crypt depth values in the jejunum were significantly higher in group B (191.41μm) and C (246.23 μm) compared with the control (145.14 μm). The jejunal V:C ratio was significantly lower in groups B and C. The study showed significant morphological changes in the intestinal parameters in rats fed predominantly with meat and bakery products. These findings could be applicable in both veterinary and human medicine, underlining the significance of consumed food on gut health.https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2025_0010dietintestinesmorphologyrats |
| spellingShingle | Nedžad Hadžiomerović Fuad Babović Anel Vejzović Aida Bešić Elvir Čičkušić Nejra Dučić Muhamed Katica The influence of different food types on the morphological characteristics of rat small intestines Macedonian Veterinary Review diet intestines morphology rats |
| title | The influence of different food types on the morphological characteristics of rat small intestines |
| title_full | The influence of different food types on the morphological characteristics of rat small intestines |
| title_fullStr | The influence of different food types on the morphological characteristics of rat small intestines |
| title_full_unstemmed | The influence of different food types on the morphological characteristics of rat small intestines |
| title_short | The influence of different food types on the morphological characteristics of rat small intestines |
| title_sort | influence of different food types on the morphological characteristics of rat small intestines |
| topic | diet intestines morphology rats |
| url | https://macvetrev.mk/LoadArticleContent?DOI=10.2478_macvetrev_2025_0010 |
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