Integrating Single‐Cell Transcriptomics and Machine Learning to Define an ac4C Gene Signature in Lung Adenocarcinoma

Integrating Single‐Cell Transcriptomics and Machine Learning to Define an ac4C Gene Signature in Lung Adenocarcinoma

ABSTRACT Introduction Lung adenocarcinoma, the most common subtype of non‐small cell lung cancer, faces challenges such as drug resistance and tumor heterogeneity. N4‐acetylcytidine (ac4C) is an important RNA modification involved in cancer progression, but its role in lung adenocarcinoma remains un...

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Bibliographic Details
Main Authors: Yuan Wang, Wei Su, Guangyao Zhou, Yijie Wang, Chunnuan Wu, Pengpeng Zhang, Lianmin Zhang
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Thoracic Cancer
Subjects:
lung cancer
machine learning
N4‐acetylcytidine
prognostic signature
RNA modification
Online Access:https://doi.org/10.1111/1759-7714.70140
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