Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction
Abdominal wall defects, including hernias and congenital anomalies, are complex conditions that require practical and durable repair strategies. While commonly used, traditional synthetic meshes often face limitations such as poor integration with host tissue and complications like infection or adh...
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| Format: | Article |
| Language: | English |
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German Journal of Pharmaceuticals and Biomaterials
2025-01-01
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| Series: | German Journal of Pharmaceuticals and Biomaterials |
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| Online Access: | https://www.gjpb.de/index.php/gjpb/article/view/172 |
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| author | Alook Kumar Ajay Shashi Ranjan Rajendra Singh Shalini Kapoor Mehta |
| author_facet | Alook Kumar Ajay Shashi Ranjan Rajendra Singh Shalini Kapoor Mehta |
| author_sort | Alook Kumar Ajay |
| collection | DOAJ |
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Abdominal wall defects, including hernias and congenital anomalies, are complex conditions that require practical and durable repair strategies. While commonly used, traditional synthetic meshes often face limitations such as poor integration with host tissue and complications like infection or adhesion formation. This paper presents hydrogel-based materials as a novel approach to addressing these abdominal wall defect repair challenges. Hydrogels, characterized by their biocompatibility, tunable mechanical properties, and ability to support tissue regeneration, offer a promising alternative to existing methods. This paper explores the design and application of these hydrogels, highlighting their potential to improve surgical outcomes through enhanced tissue integration, reduced inflammation, and minimized postoperative complications. Preclinical and clinical evidence suggests that hydrogel technology could revolutionize the standard of care for abdominal wall defects, offering a more effective and patient-friendly solution.
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| format | Article |
| id | doaj-art-9c6f8529ad60428da06c46b0ed47e18f |
| institution | Kabale University |
| issn | 2750-624X 2750-6258 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | German Journal of Pharmaceuticals and Biomaterials |
| record_format | Article |
| series | German Journal of Pharmaceuticals and Biomaterials |
| spelling | doaj-art-9c6f8529ad60428da06c46b0ed47e18f2025-02-11T06:26:19ZengGerman Journal of Pharmaceuticals and BiomaterialsGerman Journal of Pharmaceuticals and Biomaterials2750-624X2750-62582025-01-013410.5530/gjpb.2024.4.13Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall ReconstructionAlook Kumar Ajay0Shashi Ranjan1Rajendra Singh2Shalini Kapoor Mehta3Department of Medicinal Chemistry, Rajputana college of Pharmacy, Bangalore, Karnataka, India.Department of Pharmaceutical Sciences, Rajputana college of Pharmacy, Bangalore, Karnataka, India.Department of Pharmacology, Rajputana college of Pharmacy, Bangalore, Karnataka, India.Department of Phytochemistry, Rajputana college of Pharmacy, Bangalore, Karnataka, India. Abdominal wall defects, including hernias and congenital anomalies, are complex conditions that require practical and durable repair strategies. While commonly used, traditional synthetic meshes often face limitations such as poor integration with host tissue and complications like infection or adhesion formation. This paper presents hydrogel-based materials as a novel approach to addressing these abdominal wall defect repair challenges. Hydrogels, characterized by their biocompatibility, tunable mechanical properties, and ability to support tissue regeneration, offer a promising alternative to existing methods. This paper explores the design and application of these hydrogels, highlighting their potential to improve surgical outcomes through enhanced tissue integration, reduced inflammation, and minimized postoperative complications. Preclinical and clinical evidence suggests that hydrogel technology could revolutionize the standard of care for abdominal wall defects, offering a more effective and patient-friendly solution. https://www.gjpb.de/index.php/gjpb/article/view/172HydrogelAbdominal wall defectsherniaelectrospinningnanotechnologytissue regeneration |
| spellingShingle | Alook Kumar Ajay Shashi Ranjan Rajendra Singh Shalini Kapoor Mehta Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction German Journal of Pharmaceuticals and Biomaterials Hydrogel Abdominal wall defects hernia electrospinning nanotechnology tissue regeneration |
| title | Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction |
| title_full | Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction |
| title_fullStr | Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction |
| title_full_unstemmed | Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction |
| title_short | Abdominal Wall Defects: Hydrogel based solutions in Abdominal Wall Reconstruction |
| title_sort | abdominal wall defects hydrogel based solutions in abdominal wall reconstruction |
| topic | Hydrogel Abdominal wall defects hernia electrospinning nanotechnology tissue regeneration |
| url | https://www.gjpb.de/index.php/gjpb/article/view/172 |
| work_keys_str_mv | AT alookkumarajay abdominalwalldefectshydrogelbasedsolutionsinabdominalwallreconstruction AT shashiranjan abdominalwalldefectshydrogelbasedsolutionsinabdominalwallreconstruction AT rajendrasingh abdominalwalldefectshydrogelbasedsolutionsinabdominalwallreconstruction AT shalinikapoormehta abdominalwalldefectshydrogelbasedsolutionsinabdominalwallreconstruction |