Radiophobia Harm, Its Main Cause, and a Proposed Solution
Background: We are exposed to natural ionizing radiation and other genomic stressors throughout life and radiophobia has caused much harm to society. The main basis for radiophobia is the invalid linear no-threshold (LNT) hypothesis for cancer induction, which the System of Radiological Protection (...
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| Language: | English |
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SAGE Publishing
2025-02-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.1177/15593258251318305 |
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| author | Bobby R. Scott |
| author_facet | Bobby R. Scott |
| author_sort | Bobby R. Scott |
| collection | DOAJ |
| description | Background: We are exposed to natural ionizing radiation and other genomic stressors throughout life and radiophobia has caused much harm to society. The main basis for radiophobia is the invalid linear no-threshold (LNT) hypothesis for cancer induction, which the System of Radiological Protection (SRP) is linked to. Largely unknown to the public, evolution-associated genomic stress adaptation (gensadaptation) over many previous generations now provides protection to all lifeforms from low radiation doses. Objective: To help bring about an improved SRP not linked to the invalid LNT hypothesis for radiation-caused health detriment and to promote low-dose radiation therapy for different diseases. Methods: All-solid-cancer mortality risk dose-response relationships for A-bomb survivors were generated based on published LNT-modeling-related results. Dose-response relationships for lung cancer prevention by low-dose radiation were generated by linear interpolation based on published data from a study using > 15,000 mice. Uncertainty characterization was based on Monte Carlo calculations for binomial and Poisson distributions. New dose characterization tools were used for threshold dose-response relationships for radiation-caused cancer mortality. Results: The all-solid-cancer mortality risk for A-bomb survivors transitioned from LNT to threshold-linear when adjusted for key missing uncertainty at low doses. The prevention of lung cancer in mice by low radiation doses depends on the radiation absorbed dose and type. Conclusions: The SRP should be linked to population dose thresholds rather than the invalid LNT hypothesis and small likely harmless radiation doses could possibly be used in treating different diseases. |
| format | Article |
| id | doaj-art-9c6ed9fee92c4e03b1258a2ef34bb2a1 |
| institution | DOAJ |
| issn | 1559-3258 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Dose-Response |
| spelling | doaj-art-9c6ed9fee92c4e03b1258a2ef34bb2a12025-08-20T02:48:39ZengSAGE PublishingDose-Response1559-32582025-02-012310.1177/15593258251318305Radiophobia Harm, Its Main Cause, and a Proposed SolutionBobby R. ScottBackground: We are exposed to natural ionizing radiation and other genomic stressors throughout life and radiophobia has caused much harm to society. The main basis for radiophobia is the invalid linear no-threshold (LNT) hypothesis for cancer induction, which the System of Radiological Protection (SRP) is linked to. Largely unknown to the public, evolution-associated genomic stress adaptation (gensadaptation) over many previous generations now provides protection to all lifeforms from low radiation doses. Objective: To help bring about an improved SRP not linked to the invalid LNT hypothesis for radiation-caused health detriment and to promote low-dose radiation therapy for different diseases. Methods: All-solid-cancer mortality risk dose-response relationships for A-bomb survivors were generated based on published LNT-modeling-related results. Dose-response relationships for lung cancer prevention by low-dose radiation were generated by linear interpolation based on published data from a study using > 15,000 mice. Uncertainty characterization was based on Monte Carlo calculations for binomial and Poisson distributions. New dose characterization tools were used for threshold dose-response relationships for radiation-caused cancer mortality. Results: The all-solid-cancer mortality risk for A-bomb survivors transitioned from LNT to threshold-linear when adjusted for key missing uncertainty at low doses. The prevention of lung cancer in mice by low radiation doses depends on the radiation absorbed dose and type. Conclusions: The SRP should be linked to population dose thresholds rather than the invalid LNT hypothesis and small likely harmless radiation doses could possibly be used in treating different diseases.https://doi.org/10.1177/15593258251318305 |
| spellingShingle | Bobby R. Scott Radiophobia Harm, Its Main Cause, and a Proposed Solution Dose-Response |
| title | Radiophobia Harm, Its Main Cause, and a Proposed Solution |
| title_full | Radiophobia Harm, Its Main Cause, and a Proposed Solution |
| title_fullStr | Radiophobia Harm, Its Main Cause, and a Proposed Solution |
| title_full_unstemmed | Radiophobia Harm, Its Main Cause, and a Proposed Solution |
| title_short | Radiophobia Harm, Its Main Cause, and a Proposed Solution |
| title_sort | radiophobia harm its main cause and a proposed solution |
| url | https://doi.org/10.1177/15593258251318305 |
| work_keys_str_mv | AT bobbyrscott radiophobiaharmitsmaincauseandaproposedsolution |