Surface Gene Mutations of Hepatitis B Virus and Related Pathogenic Mechanisms: A Narrative Review

Surface Gene Mutations of Hepatitis B Virus and Related Pathogenic Mechanisms: A Narrative Review

Liver cancer has high incidence and mortality rates worldwide, with hepatocellular carcinoma (HCC) being the main histological subtype, accounting for 90% of primary liver cancers. The high mutation rate of viruses combined with endoplasmic reticulum stress may lead to the occurrence of cancer. Hepa...

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Bibliographic Details
Main Authors: Tingxi Yan, Yusheng Zhang, Huifang Zhou, Ning Jiang, Xiaotong Wang, Wei Yan, Jianhua Yin
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Viruses
Subjects:
hepatitis B virus
gene mutation
endoplasmic reticulum stress
unfolded protein response
Online Access:https://www.mdpi.com/1999-4915/17/7/974
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