Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome
Lichenoid drug reactions (LDRs) are a type of cutaneous adverse drug reaction that clinically resembles lichen planus and demonstrates lichenoid tissue reaction on histopathology. These have been implicated by various topical, oral, and injectable medications. Noonan’s syndrome (NS) is an autosomal...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
|
| Series: | Indian Journal of Paediatric Dermatology |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ijpd.ijpd_1_25 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849425617393549312 |
|---|---|
| author | Uffra Shaikh Swagata Tambe Kirti Jangid Prashant Patil |
| author_facet | Uffra Shaikh Swagata Tambe Kirti Jangid Prashant Patil |
| author_sort | Uffra Shaikh |
| collection | DOAJ |
| description | Lichenoid drug reactions (LDRs) are a type of cutaneous adverse drug reaction that clinically resembles lichen planus and demonstrates lichenoid tissue reaction on histopathology. These have been implicated by various topical, oral, and injectable medications. Noonan’s syndrome (NS) is an autosomal dominant disorder with skeletal deformity, particularly short stature as a common feature for which growth hormone (GH) therapy is effective. Here, we present a 16-year-old male with NS who developed lichenoid dermatitis on initiation of injectable GH therapy and showed remission with oral apremilast and after withdrawal of the injectable GH therapy. |
| format | Article |
| id | doaj-art-9c69f0a84caa44ff8e1903477b02be4e |
| institution | Kabale University |
| issn | 2319-7250 2319-7269 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Paediatric Dermatology |
| spelling | doaj-art-9c69f0a84caa44ff8e1903477b02be4e2025-08-20T03:29:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Paediatric Dermatology2319-72502319-72692025-04-0126212512810.4103/ijpd.ijpd_1_25Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s SyndromeUffra ShaikhSwagata TambeKirti JangidPrashant PatilLichenoid drug reactions (LDRs) are a type of cutaneous adverse drug reaction that clinically resembles lichen planus and demonstrates lichenoid tissue reaction on histopathology. These have been implicated by various topical, oral, and injectable medications. Noonan’s syndrome (NS) is an autosomal dominant disorder with skeletal deformity, particularly short stature as a common feature for which growth hormone (GH) therapy is effective. Here, we present a 16-year-old male with NS who developed lichenoid dermatitis on initiation of injectable GH therapy and showed remission with oral apremilast and after withdrawal of the injectable GH therapy.https://journals.lww.com/10.4103/ijpd.ijpd_1_25growth hormonelichenoid drug reactionsnoonan’s syndrome |
| spellingShingle | Uffra Shaikh Swagata Tambe Kirti Jangid Prashant Patil Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome Indian Journal of Paediatric Dermatology growth hormone lichenoid drug reactions noonan’s syndrome |
| title | Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome |
| title_full | Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome |
| title_fullStr | Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome |
| title_full_unstemmed | Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome |
| title_short | Lichenoid Drug Eruption Secondary to Growth Hormone in a Case of Noonan’s Syndrome |
| title_sort | lichenoid drug eruption secondary to growth hormone in a case of noonan s syndrome |
| topic | growth hormone lichenoid drug reactions noonan’s syndrome |
| url | https://journals.lww.com/10.4103/ijpd.ijpd_1_25 |
| work_keys_str_mv | AT uffrashaikh lichenoiddrugeruptionsecondarytogrowthhormoneinacaseofnoonanssyndrome AT swagatatambe lichenoiddrugeruptionsecondarytogrowthhormoneinacaseofnoonanssyndrome AT kirtijangid lichenoiddrugeruptionsecondarytogrowthhormoneinacaseofnoonanssyndrome AT prashantpatil lichenoiddrugeruptionsecondarytogrowthhormoneinacaseofnoonanssyndrome |