The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.

The innate immune response elicited by Group A Streptococcus is highly variable among clinical isolates and correlates with the emm type.

Group A Streptococcus (GAS) infections remain a significant health care problem due to high morbidity and mortality associated with GAS diseases, along with their increasing worldwide prevalence. Macrophages play a key role in the control and clearance of GAS infections. Moreover, pro-inflammatory c...

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Main Authors: Márcia Dinis, Céline Plainvert, Pavel Kovarik, Magalie Longo, Agnès Fouet, Claire Poyart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0101464
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