Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report
Introduction: Patients with short bowel syndrome (SBS) on conventional oral diets often face nutritional deficiencies and dehydration, a challenge further compounded during pregnancy. This case report describes the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional managem...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2025-02-01
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| Series: | Case Reports in Gastroenterology |
| Online Access: | https://karger.com/article/doi/10.1159/000543291 |
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| author | Maria M. Dahar MacKenzie Both Linda M. Lord Carly Densmore Lawrence J. Saubermann |
| author_facet | Maria M. Dahar MacKenzie Both Linda M. Lord Carly Densmore Lawrence J. Saubermann |
| author_sort | Maria M. Dahar |
| collection | DOAJ |
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Introduction: Patients with short bowel syndrome (SBS) on conventional oral diets often face nutritional deficiencies and dehydration, a challenge further compounded during pregnancy. This case report describes the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional management of an SBS patient dependent on total parenteral nutrition (TPN). Case Presentation: A 29-year-old woman with a significant medical history of Crohn’s disease leading to SBS was traditionally dependent on TPN for sustenance. During her pregnancy, she was successfully managed with a GLP-2 analog, which enabled her to wean off TPN. This successful management underscores the therapeutic potential of GLP-2 analogs in effectively altering the nutritional landscape for SBS patients, including during the physiologically demanding period of pregnancy. Conclusion: GLP-2 analogs helped with the nutritional management of patients with SBS during pregnancy and helped them wean off TPN. There is a need for further research and exploration into GLP-2 analogs as viable alternatives to conventional treatments such as TPN in the care and management of SBS patients during pregnancy. |
| format | Article |
| id | doaj-art-9c56ac4092e841a8b15cea99f683c2bf |
| institution | Kabale University |
| issn | 1662-0631 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Gastroenterology |
| spelling | doaj-art-9c56ac4092e841a8b15cea99f683c2bf2025-08-20T03:49:41ZengKarger PublishersCase Reports in Gastroenterology1662-06312025-02-01191576110.1159/000543291Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case ReportMaria M. DaharMacKenzie BothLinda M. LordCarly DensmoreLawrence J. Saubermann Introduction: Patients with short bowel syndrome (SBS) on conventional oral diets often face nutritional deficiencies and dehydration, a challenge further compounded during pregnancy. This case report describes the use of a glucagon-like peptide-2 (GLP-2) analog in the nutritional management of an SBS patient dependent on total parenteral nutrition (TPN). Case Presentation: A 29-year-old woman with a significant medical history of Crohn’s disease leading to SBS was traditionally dependent on TPN for sustenance. During her pregnancy, she was successfully managed with a GLP-2 analog, which enabled her to wean off TPN. This successful management underscores the therapeutic potential of GLP-2 analogs in effectively altering the nutritional landscape for SBS patients, including during the physiologically demanding period of pregnancy. Conclusion: GLP-2 analogs helped with the nutritional management of patients with SBS during pregnancy and helped them wean off TPN. There is a need for further research and exploration into GLP-2 analogs as viable alternatives to conventional treatments such as TPN in the care and management of SBS patients during pregnancy. https://karger.com/article/doi/10.1159/000543291 |
| spellingShingle | Maria M. Dahar MacKenzie Both Linda M. Lord Carly Densmore Lawrence J. Saubermann Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report Case Reports in Gastroenterology |
| title | Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report |
| title_full | Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report |
| title_fullStr | Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report |
| title_full_unstemmed | Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report |
| title_short | Successful Pregnancy in a Patient with Crohn’s Disease and Short Bowel Syndrome: Off Total Parenteral Nutrition and On Teduglutide, a Glucagon-Like Peptide-2 Analog – A Case Report |
| title_sort | successful pregnancy in a patient with crohn s disease and short bowel syndrome off total parenteral nutrition and on teduglutide a glucagon like peptide 2 analog a case report |
| url | https://karger.com/article/doi/10.1159/000543291 |
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