Tripterhyponoid A from <i>Tripterygium hypoglaucum</i> Inhibiting MRSA by Multiple Mechanisms

Tripterhyponoid A from <i>Tripterygium hypoglaucum</i> Inhibiting MRSA by Multiple Mechanisms

The emergence of methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) and its biofilm-forming ability underscore the limitations of current antibiotics. In this study, a new compound named tripterhyponoid A was found to effectively combat MRSA, with an MIC of 2.0 μg/mL. It inhibited...

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Bibliographic Details
Main Authors: Yan-Yan Zhu, Qiong Jin, Zhao-Jie Wang, Mei-Zhen Wei, Wen-Biao Zu, Zhong-Shun Zhou, Bin-Yuan Hu, Yun-Li Zhao, Xu-Jie Qin, Xiao-Dong Luo
Format: Article
Language:English
Published: MDPI AG 2025-06-01
Series:Molecules
Subjects:
tripterhyponoid A
anti-MRSA
quorum sensing
antibiofilm
DNA binding
Online Access:https://www.mdpi.com/1420-3049/30/12/2539
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